Regorafenib

Name: Regorafenib
Brand: Vaqora Chemicals
SKU: VQ-007701

About Regorafenib

Vaqora Chemicals supplies Regorafenib, a high-purity reference standard of Regorafenib registered under CAS number 755037-03-7. With the molecular formula C21H15ClF4N4O3, it has a molar mass of 482.8 g/mol. Systematically, it is named 4-[4-[[4-chloro-3-(trifluoromethyl)phenyl]carbamoylamino]-3-fluorophenoxy]-N-methylpyridine-2-carboxamide. Common synonyms include Stivarga and Stivargo.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Handle it with standard laboratory precautions and appropriate personal protective equipment.

Laboratories use this Regorafenib standard for identity and assay testing, system suitability checks and method validation supporting ANDA and DMF filings. It is used across pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Regorafenib in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Regorafenib

View every impurity, metabolite and intermediate we list for Regorafenib.

Regorafenib impurities

Specifications & identifiers

Chemical identifiers
Product name	Regorafenib
Catalogue No.	VQ-007701
CAS Number	755037-03-7
Other CAS	1019206-88-2
IUPAC name	4-[4-[[4-chloro-3-(trifluoromethyl)phenyl]carbamoylamino]-3-fluorophenoxy]-N-methylpyridine-2-carboxamide
Molecular formula	C₂₁H₁₅ClF₄N₄O₃
Molecular weight	482.8 g/mol
Exact mass	482.0769
Grade	Reference Standard
HSN code	38229090
InChIKey	FNHKPVJBJVTLMP-UHFFFAOYSA-N
SMILES	CNC(=O)C1=NC=CC(=C1)OC2=CC(=C(C=C2)NC(=O)NC3=CC(=C(C=C3)Cl)C(F)(F)F)F
PubChem CID	11167602

Physical properties
Physical form	Solid
LogP (XLogP3)	4.2
H-bond donors / acceptors	3 / 8
TPSA	92.4 Å²
Synonyms	4-(4-(3-(4-chloro-3-(trifluoromethyl)phenyl)ureido)-3-fluorophenoxy)-N-methylpicolinamide, Stivarga, Stivargo, BAY-734506 monohydrate, BAY 73-4506 monohydrate, Regorafenib (BAY 73-4506), C21H15ClF4N4O3, Regorafenib,BAY 73-4506, Stivarga (TN), Regorafenib (Standard), A1JCR, 2-Pyridinecarboxamide,4

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Regorafenib?

The CAS Registry Number of Regorafenib is 755037-03-7. It is also known as 4-(4-(3-(4-chloro-3-(trifluoromethyl)phenyl)ureido)-3-fluorophenoxy)-N-methylpicolinamide, Stivarga, Stivargo.

What is the molecular formula and molecular weight of Regorafenib?

Regorafenib has the molecular formula C21H15ClF4N4O3 and a molecular weight of 482.8 g/mol. Its IUPAC name is 4-[4-[[4-chloro-3-(trifluoromethyl)phenyl]carbamoylamino]-3-fluorophenoxy]-N-methylpyridine-2-carboxamide.

What is Regorafenib used for?

Regorafenib is supplied as a characterised reference material related to Regorafenib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Regorafenib can I order?

We supply Regorafenib in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Regorafenib?

Yes. Every lot of Regorafenib is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Regorafenib be shipped internationally?

Yes. We export Regorafenib worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.