Regorafenib Monohydrate

Name: Regorafenib Monohydrate
Brand: Vaqora Chemicals
SKU: VQ-007702

About Regorafenib Monohydrate

Regorafenib Monohydrate is a high-purity reference standard of Regorafenib carrying the CAS registry number 1019206-88-2. The compound has the formula C21H17ClF4N4O4, corresponding to a molecular weight of 500.8 g/mol. Alternative names: Regorafenib hydrate and Regorafenib (monohydrate).

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. It carries the GHS signal word “Danger” with 5 hazard statements. Review the Safety Data Sheet before use.

As a reference sample of Regorafenib, it is used for identification, assay and impurity-profiling work during analytical method development, validation (AMV) and routine QC. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Regorafenib Monohydrate in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide. This item is currently in stock for prompt dispatch.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Regorafenib

View every impurity, metabolite and intermediate we list for Regorafenib.

Regorafenib impurities

Specifications & identifiers

Chemical identifiers
Product name	Regorafenib Monohydrate
Catalogue No.	VQ-007702
CAS Number	1019206-88-2
Other CAS	755037-03-7
IUPAC name	4-[4-[[4-chloro-3-(trifluoromethyl)phenyl]carbamoylamino]-3-fluorophenoxy]-N-methylpyridine-2-carboxamide;hydrate
Molecular formula	C₂₁H₁₇ClF₄N₄O₄
Molecular weight	500.8 g/mol
Exact mass	500.0874
Grade	Reference Standard
HSN code	38229090
InChIKey	ZOPOQLDXFHBOIH-UHFFFAOYSA-N
SMILES	CNC(=O)C1=NC=CC(=C1)OC2=CC(=C(C=C2)NC(=O)NC3=CC(=C(C=C3)Cl)C(F)(F)F)F.O
PubChem CID	24768591

Physical properties
Physical form	Solid
H-bond donors / acceptors	4 / 9
TPSA	93.4 Å²
Synonyms	Regorafenib hydrate, Regorafenib (monohydrate), Regorafenib (BAY-734506) Monohydrate, Stivarga (TN), Regorafenib hydrate (JAN), C21H17ClF4N4O4, Regorafenib monohydrate CRS, BAY 73-4506 (monohydrate), EX-A058-1, Regorafenib (monohydrate) (Standard), Regorafenib monohydrateBAY 73-4506, Regorafenib monohydrateBAY 73-4506?

Safety & hazard information (GHS)

Health hazard

Environmental hazard

Signal word: Danger

Hazard statements

H362May cause harm to breast-fed children
H372Causes damage to organs through prolonged or repeated exposure
H373May causes damage to organs through prolonged or repeated exposure
H400Very toxic to aquatic life
H410Very toxic to aquatic life with long lasting effects

Precautionary statements: P203, P260, P263, P264, P270, P273, P280, P318, P319, P391, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Regorafenib Monohydrate?

The CAS Registry Number of Regorafenib Monohydrate is 1019206-88-2. It is also known as Regorafenib hydrate, Regorafenib (monohydrate), Regorafenib (BAY-734506) Monohydrate.

What is the molecular formula and molecular weight of Regorafenib Monohydrate?

Regorafenib Monohydrate has the molecular formula C21H17ClF4N4O4 and a molecular weight of 500.8 g/mol.

What is Regorafenib Monohydrate used for?

Regorafenib Monohydrate is supplied as a characterised reference material related to Regorafenib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Regorafenib Monohydrate can I order?

We supply Regorafenib Monohydrate in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Regorafenib Monohydrate?

Yes. Every lot of Regorafenib Monohydrate is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Regorafenib Monohydrate be shipped internationally?

Yes. Regorafenib Monohydrate is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.