Regorafenib Desmethyl Impurity

Name: Regorafenib Desmethyl Impurity
Brand: Vaqora Chemicals
SKU: VQ-007245

About Regorafenib Desmethyl Impurity

Regorafenib Desmethyl Impurity (CAS 1343498-72-5) is a metabolite or degradation product of Regorafenib offered by Vaqora Chemicals, specified at 91% purity. Its molecular formula is C20H13ClF4N4O3 and its molecular weight is 468.8 g/mol. The IUPAC name is 4-[4-[[4-chloro-3-(trifluoromethyl)phenyl]carbamoylamino]-3-fluorophenoxy]pyridine-2-carboxamide. It is also known as N-Desmethyl Regorafenib or Regorafenib metabolite M4.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Good laboratory practice and suitable PPE are recommended during handling.

Analytical teams use this compound to identify metabolites and degradants of Regorafenib, to validate stability-indicating methods (AMV) and to support QC and regulatory filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Regorafenib Desmethyl Impurity is dispatched with a Certificate of Analysis (COA) to destinations worldwide. Stock is available for quick dispatch.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Regorafenib

View every impurity, metabolite and intermediate we list for Regorafenib.

Regorafenib impurities

Specifications & identifiers

Chemical identifiers
Product name	Regorafenib Desmethyl Impurity
Catalogue No.	VQ-007245
CAS Number	1343498-72-5
IUPAC name	4-[4-[[4-chloro-3-(trifluoromethyl)phenyl]carbamoylamino]-3-fluorophenoxy]pyridine-2-carboxamide
Molecular formula	C₂₀H₁₃ClF₄N₄O₃
Molecular weight	468.8 g/mol
Exact mass	468.0612
Grade	Reference Standard
Purity / assay	91%
HSN code	38229090
InChIKey	UJAPQTJRMGFPQS-UHFFFAOYSA-N
SMILES	C1=CC(=C(C=C1NC(=O)NC2=C(C=C(C=C2)OC3=CC(=NC=C3)C(=O)N)F)C(F)(F)F)Cl
PubChem CID	53491672

Physical properties
Physical form	Solid
LogP (XLogP3)	3.8
H-bond donors / acceptors	3 / 8
TPSA	106 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Regorafenib Desmethyl Impurity?

The CAS Registry Number of Regorafenib Desmethyl Impurity is 1343498-72-5. It is also known as N-Desmethyl Regorafenib, 4-(4-(3-(4-chloro-3-(trifluoromethyl)phenyl)ureido)-3-fluorophenoxy)picolinamide, Regorafenib metabolite M4.

What is the molecular formula and molecular weight of Regorafenib Desmethyl Impurity?

Regorafenib Desmethyl Impurity has the molecular formula C20H13ClF4N4O3 and a molecular weight of 468.8 g/mol. Its IUPAC name is 4-[4-[[4-chloro-3-(trifluoromethyl)phenyl]carbamoylamino]-3-fluorophenoxy]pyridine-2-carboxamide.

What is Regorafenib Desmethyl Impurity used for?

Regorafenib Desmethyl Impurity is supplied as a characterised reference material related to Regorafenib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Regorafenib Desmethyl Impurity can I order?

We supply Regorafenib Desmethyl Impurity in Reference Standard (91%) grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Regorafenib Desmethyl Impurity?

Yes. Every lot of Regorafenib Desmethyl Impurity is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Regorafenib Desmethyl Impurity be shipped internationally?

Yes. We export Regorafenib Desmethyl Impurity worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.