Regorafenib N-Oxide

Name: Regorafenib N-Oxide
Brand: Vaqora Chemicals
SKU: VQ-007246

About Regorafenib N-Oxide

Vaqora Chemicals supplies Regorafenib N-Oxide, a metabolite or degradation product of Regorafenib registered under CAS number 835621-11-9. Its molecular formula is C21H15ClF4N4O4 and its molecular weight is 498.8 g/mol. Alternative names: Regorafenib (Pyridine)-N-oxide and Regoraf |nib N-oxyde (M2).

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Good laboratory practice and suitable PPE are recommended during handling.

It is used in metabolite identification, stability-indicating method development and impurity profiling of Regorafenib, as well as in QC testing and ANDA/DMF documentation. It is used across pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Regorafenib N-Oxide is dispatched with a Certificate of Analysis (COA) to destinations worldwide. Stock is available for quick dispatch.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Regorafenib

View every impurity, metabolite and intermediate we list for Regorafenib.

Regorafenib impurities

Specifications & identifiers

Chemical identifiers
Product name	Regorafenib N-Oxide
Catalogue No.	VQ-007246
CAS Number	835621-11-9
IUPAC name	4-[4-[[4-chloro-3-(trifluoromethyl)phenyl]carbamoylamino]-3-fluorophenoxy]-N-methyl-1-oxidopyridin-1-ium-2-carboxamide
Molecular formula	C₂₁H₁₅ClF₄N₄O₄
Molecular weight	498.8 g/mol
Exact mass	498.0718
Grade	Reference Standard
HSN code	38229090
InChIKey	NUCXNEKIESREQY-UHFFFAOYSA-N
SMILES	CNC(=O)C1=[N+](C=CC(=C1)OC2=CC(=C(C=C2)NC(=O)NC3=CC(=C(C=C3)Cl)C(F)(F)F)F)[O-]
PubChem CID	53491674

Physical properties
Physical form	Solid
LogP (XLogP3)	3.7
H-bond donors / acceptors	3 / 8
TPSA	105 Å²
Synonyms	Regorafenib (Pyridine)-N-oxide, Regoraf, nib N-oxyde (M2), Regorafenib metabolite M2, Regorafenib N-Oxide(M2), Regorafenib N-oxide (M2 Metabolite), Regorafenib N-oxyde (M2), Regorafenib Pyridine-N-Oxide, Regorafenib metabolite M2 oxide, CS-M2818

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Regorafenib N-Oxide?

The CAS Registry Number of Regorafenib N-Oxide is 835621-11-9. It is also known as Regorafenib (Pyridine)-N-oxide, Regoraf, nib N-oxyde (M2).

What is the molecular formula and molecular weight of Regorafenib N-Oxide?

Regorafenib N-Oxide has the molecular formula C21H15ClF4N4O4 and a molecular weight of 498.8 g/mol. Its IUPAC name is 4-[4-[[4-chloro-3-(trifluoromethyl)phenyl]carbamoylamino]-3-fluorophenoxy]-N-methyl-1-oxidopyridin-1-ium-2-carboxamide.

What is Regorafenib N-Oxide used for?

Regorafenib N-Oxide is supplied as a characterised reference material related to Regorafenib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Regorafenib N-Oxide can I order?

We supply Regorafenib N-Oxide in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Regorafenib N-Oxide?

Yes. Every lot of Regorafenib N-Oxide is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Regorafenib N-Oxide be shipped internationally?

Yes. We export Regorafenib N-Oxide worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.