Regorafenib Chloro Trifluoro Aniline Impurity

Name: Regorafenib Chloro Trifluoro Aniline Impurity
Brand: Vaqora Chemicals
SKU: VQ-005717

About Regorafenib Chloro Trifluoro Aniline Impurity

Regorafenib Chloro Trifluoro Aniline Impurity (CAS 320-51-4) is an impurity of Regorafenib offered by Vaqora Chemicals. Its molecular formula is C7H5ClF3N and its molecular weight is 195.57 g/mol. Its systematic (IUPAC) name is 4-chloro-3-(trifluoromethyl)aniline. Alternative names: Regorafenib Impurity IV and 5-Amino-2-chlorobenzotrifluoride.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

This Regorafenib impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. It is used across pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Regorafenib Chloro Trifluoro Aniline Impurity is dispatched with a Certificate of Analysis (COA) to destinations worldwide. Stock is available for quick dispatch.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Regorafenib

View every impurity, metabolite and intermediate we list for Regorafenib.

Regorafenib impurities

Specifications & identifiers

Chemical identifiers
Product name	Regorafenib Chloro Trifluoro Aniline Impurity
Catalogue No.	VQ-005717
CAS Number	320-51-4
IUPAC name	4-chloro-3-(trifluoromethyl)aniline
Molecular formula	C₇H₅ClF₃N
Molecular weight	195.57 g/mol
Exact mass	195.0063
Grade	Reference Standard
HSN code	38229090
InChIKey	ASPDJZINBYYZRU-UHFFFAOYSA-N
SMILES	C1=CC(=C(C=C1N)C(F)(F)F)Cl
PubChem CID	67574

Physical properties
Physical form	Solid
LogP (XLogP3)	3.5
H-bond donors / acceptors	1 / 4
TPSA	26 Å²
Synonyms	Regorafenib Impurity IV, 5-Amino-2-chlorobenzotrifluoride, 4-Chloro-3-(trifluoromethyl)-benzenamine, (4-Chloro-3-trifluoromethylphenyl)amine, 2-Chloro-5-aminobenzotrifluoride, 3-(Trifluoromethyl)-4-chloroaniline, 3-Amino-6-chlorobenzotrifluoride, 4-Chloro-3-(trifluoromethyl)benzenamine, 4-Chloro-alpha,alpha,alpha-trifluoro-m-toluidine, Benzenamine, 4-chloro-3-(trifluoromethyl)-, 6-Chloro-3-aminobenzotrifluoride, 4-Chloro-3-trifluoromethylaniline

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H312Harmful in contact with skin
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P317, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Other grades of CAS 320-51-4

4-Chloro-3-(trifluoromethyl)aniline, 98%

CAS: 320-51-4
Formula: C₇H₅ClF₃N
MW: 195.57 g/mol

VQ-010651

Frequently asked questions

What is the CAS number of Regorafenib Chloro Trifluoro Aniline Impurity?

The CAS Registry Number of Regorafenib Chloro Trifluoro Aniline Impurity is 320-51-4. It is also known as Regorafenib Impurity IV, 5-Amino-2-chlorobenzotrifluoride, 4-Chloro-3-(trifluoromethyl)-benzenamine.

What is the molecular formula and molecular weight of Regorafenib Chloro Trifluoro Aniline Impurity?

Regorafenib Chloro Trifluoro Aniline Impurity has the molecular formula C7H5ClF3N and a molecular weight of 195.57 g/mol. Its IUPAC name is 4-chloro-3-(trifluoromethyl)aniline.

What is Regorafenib Chloro Trifluoro Aniline Impurity used for?

Regorafenib Chloro Trifluoro Aniline Impurity is supplied as a characterised reference material related to Regorafenib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Regorafenib Chloro Trifluoro Aniline Impurity can I order?

We supply Regorafenib Chloro Trifluoro Aniline Impurity in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Regorafenib Chloro Trifluoro Aniline Impurity?

Yes. Every lot of Regorafenib Chloro Trifluoro Aniline Impurity is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Regorafenib Chloro Trifluoro Aniline Impurity be shipped internationally?

Yes. Regorafenib Chloro Trifluoro Aniline Impurity is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.