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Pharmacopeial Impurities (EP / USP / BP)Reference Standard In stock

Sorafenib EP Impurity A

Synonyms: 4-(4-Aminophenoxy)-N-methylpicolinamide · 4-(4-Aminophenoxy)-N-methyl-2-pyridinecarboxamide · 4-[2-(N-Methylcarbamyl)-4-pyridyloxy]aniline · [4-(4-Aminophenoxy)(2-pyridyl)]-N-methylcarboxamide

CAS No.284462-37-9
FormulaC13H13N3O2
Mol. weight243.26
Catalogue No.VQ-006696
PurityReference Standard
HSN38229090

Sorafenib EP Impurity A (CAS 284462-37-9) – Sorafenib impurity standard. C13H13N3O2, MW 243.26. Order from Vaqora Chemicals with COA and global delivery.

Pack sizesPrice on quotation · bulk available
10 mg
25 mg
50 mg
100 mg
250 mg
500 mg
1 g
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16-section GHS SDS
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About Sorafenib EP Impurity A

Sorafenib EP Impurity A is a pharmacopeial impurity of Sorafenib carrying the CAS registry number 284462-37-9. Its molecular formula is C13H13N3O2 and its molecular weight is 243.26 g/mol. The IUPAC name is 4-(4-aminophenoxy)-N-methylpyridine-2-carboxamide. It is also known as 4-(4-Aminophenoxy)-N-methylpicolinamide or 4-[2-(N-Methylcarbamyl)-4-pyridyloxy]aniline.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

Pharmaceutical QC and development laboratories use this impurity standard of Sorafenib to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Sorafenib EP Impurity A is dispatched with a Certificate of Analysis (COA) to destinations worldwide. This item is currently in stock for prompt dispatch.

Typical applications

  • Pharmacopeial method verification
  • Impurity profiling
  • QC release testing
  • ANDA / DMF filings

Industries

Related to Sorafenib

View every impurity, metabolite and intermediate we list for Sorafenib.

Sorafenib impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product nameSorafenib EP Impurity A
Catalogue No.VQ-006696
CAS Number284462-37-9
IUPAC name4-(4-aminophenoxy)-N-methylpyridine-2-carboxamide
Molecular formulaC13H13N3O2
Molecular weight243.26 g/mol
Exact mass243.1008
GradeReference Standard
HSN code38229090
InChIKeyRXZZBPYPZLAEFC-UHFFFAOYSA-N
SMILESCNC(=O)C1=NC=CC(=C1)OC2=CC=C(C=C2)N
PubChem CID16655129
Physical properties
Physical formSolid
LogP (XLogP3)1.3
H-bond donors / acceptors2 / 4
TPSA77.2 Ų
Synonyms4-(4-Aminophenoxy)-N-methylpicolinamide, 4-(4-Aminophenoxy)-N-methyl-2-pyridinecarboxamide, 4-[2-(N-Methylcarbamyl)-4-pyridyloxy]aniline, [4-(4-Aminophenoxy)(2-pyridyl)]-N-methylcarboxamide, N-Methyl-4-(4-aminophenoxy)pyridine-2-carboxamide, 2-Pyridinecarboxamide, 4-(4-aminophenoxy)-N-methyl-, 4-(4-amino-phenoxy)-pyridine-2-carboxylic acid methylamide, Sorafenib Tosylate Impurity A, 4-(4-amino-phenoxy)-pyridine-2-carboxylicacidmethylamide, 4-(2-(N-methylcarbarnoyl)-4-pyridyloxy)aniline, 4-(4-aminophenoxy)-N-methyl-pyridine-2-carboxamide, 4-(2-(N-methylcarbamoyl)-4-pyridyloxy)aniline

Safety & hazard information (GHS)

GHS07 Harmful / irritant
Harmful / irritant
GHS08 Health hazard
Health hazard
GHS09 Environmental hazard
Environmental hazard

Signal word: Warning

Hazard statements

  • H302Harmful if swallowed
  • H315Causes skin irritation
  • H319Causes serious eye irritation
  • H335May cause respiratory irritation
  • H341Suspected of causing genetic defects
  • H411Toxic to aquatic life with long lasting effects

Precautionary statements: P203, P261, P264, P264 + P265, P270, P271, P273, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P318, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P391, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Frequently asked questions

What is the CAS number of Sorafenib EP Impurity A?

The CAS Registry Number of Sorafenib EP Impurity A is 284462-37-9. It is also known as 4-(4-Aminophenoxy)-N-methylpicolinamide, 4-(4-Aminophenoxy)-N-methyl-2-pyridinecarboxamide, 4-[2-(N-Methylcarbamyl)-4-pyridyloxy]aniline.

What is the molecular formula and molecular weight of Sorafenib EP Impurity A?

Sorafenib EP Impurity A has the molecular formula C13H13N3O2 and a molecular weight of 243.26 g/mol. Its IUPAC name is 4-(4-aminophenoxy)-N-methylpyridine-2-carboxamide.

What is Sorafenib EP Impurity A used for?

Sorafenib EP Impurity A is supplied as a characterised reference material related to Sorafenib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Sorafenib EP Impurity A can I order?

We supply Sorafenib EP Impurity A in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg, 500 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Sorafenib EP Impurity A?

Yes. Every lot of Sorafenib EP Impurity A is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Sorafenib EP Impurity A be shipped internationally?

Yes. Sorafenib EP Impurity A is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.

Enquire about Sorafenib EP Impurity A

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Why buyers choose Vaqora

  • Batch-traceable lots with COA
  • R&D packs to multi-tonne supply
  • IATA / IMDG dangerous-goods packing
  • EXW, FOB, CIF, DAP Incoterms
  • Custom synthesis & sourcing
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