Sorafenib EP Impurity A
Synonyms: 4-(4-Aminophenoxy)-N-methylpicolinamide · 4-(4-Aminophenoxy)-N-methyl-2-pyridinecarboxamide · 4-[2-(N-Methylcarbamyl)-4-pyridyloxy]aniline · [4-(4-Aminophenoxy)(2-pyridyl)]-N-methylcarboxamide
Sorafenib EP Impurity A (CAS 284462-37-9) – Sorafenib impurity standard. C13H13N3O2, MW 243.26. Order from Vaqora Chemicals with COA and global delivery.
About Sorafenib EP Impurity A
Sorafenib EP Impurity A is a pharmacopeial impurity of Sorafenib carrying the CAS registry number 284462-37-9. Its molecular formula is C13H13N3O2 and its molecular weight is 243.26 g/mol. The IUPAC name is 4-(4-aminophenoxy)-N-methylpyridine-2-carboxamide. It is also known as 4-(4-Aminophenoxy)-N-methylpicolinamide or 4-[2-(N-Methylcarbamyl)-4-pyridyloxy]aniline.
The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.
Pharmaceutical QC and development laboratories use this impurity standard of Sorafenib to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.
Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Sorafenib EP Impurity A is dispatched with a Certificate of Analysis (COA) to destinations worldwide. This item is currently in stock for prompt dispatch.
Typical applications
- Pharmacopeial method verification
- Impurity profiling
- QC release testing
- ANDA / DMF filings
Industries
View every impurity, metabolite and intermediate we list for Sorafenib.
Sorafenib impuritiesGrade guides
Specifications & identifiers
| Product name | Sorafenib EP Impurity A |
|---|---|
| Catalogue No. | VQ-006696 |
| CAS Number | 284462-37-9 |
| IUPAC name | 4-(4-aminophenoxy)-N-methylpyridine-2-carboxamide |
| Molecular formula | C13H13N3O2 |
| Molecular weight | 243.26 g/mol |
| Exact mass | 243.1008 |
| Grade | Reference Standard |
| HSN code | 38229090 |
| InChIKey | RXZZBPYPZLAEFC-UHFFFAOYSA-N |
| SMILES | CNC(=O)C1=NC=CC(=C1)OC2=CC=C(C=C2)N |
| PubChem CID | 16655129 |
| Physical form | Solid |
|---|---|
| LogP (XLogP3) | 1.3 |
| H-bond donors / acceptors | 2 / 4 |
| TPSA | 77.2 Ų |
| Synonyms | 4-(4-Aminophenoxy)-N-methylpicolinamide, 4-(4-Aminophenoxy)-N-methyl-2-pyridinecarboxamide, 4-[2-(N-Methylcarbamyl)-4-pyridyloxy]aniline, [4-(4-Aminophenoxy)(2-pyridyl)]-N-methylcarboxamide, N-Methyl-4-(4-aminophenoxy)pyridine-2-carboxamide, 2-Pyridinecarboxamide, 4-(4-aminophenoxy)-N-methyl-, 4-(4-amino-phenoxy)-pyridine-2-carboxylic acid methylamide, Sorafenib Tosylate Impurity A, 4-(4-amino-phenoxy)-pyridine-2-carboxylicacidmethylamide, 4-(2-(N-methylcarbarnoyl)-4-pyridyloxy)aniline, 4-(4-aminophenoxy)-N-methyl-pyridine-2-carboxamide, 4-(2-(N-methylcarbamoyl)-4-pyridyloxy)aniline |
Safety & hazard information (GHS)
Signal word: Warning
Hazard statements
H302Harmful if swallowedH315Causes skin irritationH319Causes serious eye irritationH335May cause respiratory irritationH341Suspected of causing genetic defectsH411Toxic to aquatic life with long lasting effects
Precautionary statements: P203, P261, P264, P264 + P265, P270, P271, P273, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P318, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P391, P403 + P233, P405, P501
Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.
Documents
Frequently asked questions
What is the CAS number of Sorafenib EP Impurity A?
The CAS Registry Number of Sorafenib EP Impurity A is 284462-37-9. It is also known as 4-(4-Aminophenoxy)-N-methylpicolinamide, 4-(4-Aminophenoxy)-N-methyl-2-pyridinecarboxamide, 4-[2-(N-Methylcarbamyl)-4-pyridyloxy]aniline.
What is the molecular formula and molecular weight of Sorafenib EP Impurity A?
Sorafenib EP Impurity A has the molecular formula C13H13N3O2 and a molecular weight of 243.26 g/mol. Its IUPAC name is 4-(4-aminophenoxy)-N-methylpyridine-2-carboxamide.
What is Sorafenib EP Impurity A used for?
Sorafenib EP Impurity A is supplied as a characterised reference material related to Sorafenib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.
Which grade and pack sizes of Sorafenib EP Impurity A can I order?
We supply Sorafenib EP Impurity A in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg, 500 mg packs. Larger bulk quantities and custom packing are quoted on request.
Do you provide a COA and SDS with Sorafenib EP Impurity A?
Yes. Every lot of Sorafenib EP Impurity A is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.
Can Sorafenib EP Impurity A be shipped internationally?
Yes. Sorafenib EP Impurity A is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.
Enquire about Sorafenib EP Impurity A
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