Sorafenib N-Oxide

Name: Sorafenib N-Oxide
Brand: Vaqora Chemicals
SKU: VQ-007261

About Sorafenib N-Oxide

Listed under CAS 583840-03-3, Sorafenib N-Oxide is a metabolite or degradation product of Sorafenib available from Vaqora Chemicals with a typical assay of 91.55%. Formula C21H16ClF3N4O4, molecular weight 480.8 g/mol. Its systematic (IUPAC) name is 4-[4-[[4-chloro-3-(trifluoromethyl)phenyl]carbamoylamino]phenoxy]-N-methyl-1-oxidopyridin-1-ium-2-carboxamide. Common synonyms include Srf-nox and Sorafenib N oxide.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Good laboratory practice and suitable PPE are recommended during handling.

It is used in metabolite identification, stability-indicating method development and impurity profiling of Sorafenib, as well as in QC testing and ANDA/DMF documentation. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

We offer Sorafenib N-Oxide in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide. Stock is available for quick dispatch.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Sorafenib

View every impurity, metabolite and intermediate we list for Sorafenib.

Sorafenib impurities

Specifications & identifiers

Chemical identifiers
Product name	Sorafenib N-Oxide
Catalogue No.	VQ-007261
CAS Number	583840-03-3
IUPAC name	4-[4-[[4-chloro-3-(trifluoromethyl)phenyl]carbamoylamino]phenoxy]-N-methyl-1-oxidopyridin-1-ium-2-carboxamide
Molecular formula	C₂₁H₁₆ClF₃N₄O₄
Molecular weight	480.8 g/mol
Exact mass	480.0812
Grade	Reference Standard
Purity / assay	91.55%
HSN code	38229090
InChIKey	BQAZCCVUZDIZDC-UHFFFAOYSA-N
SMILES	CNC(=O)C1=[N+](C=CC(=C1)OC2=CC=C(C=C2)NC(=O)NC3=CC(=C(C=C3)Cl)C(F)(F)F)[O-]
PubChem CID	9826472

Physical properties
Physical form	Solid
LogP (XLogP3)	3.6
H-bond donors / acceptors	3 / 7
TPSA	105 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Sorafenib N-Oxide?

The CAS Registry Number of Sorafenib N-Oxide is 583840-03-3. It is also known as Srf-nox, Sorafenib N oxide, Sorafenib metabolite M2.

What is the molecular formula and molecular weight of Sorafenib N-Oxide?

Sorafenib N-Oxide has the molecular formula C21H16ClF3N4O4 and a molecular weight of 480.8 g/mol. Its IUPAC name is 4-[4-[[4-chloro-3-(trifluoromethyl)phenyl]carbamoylamino]phenoxy]-N-methyl-1-oxidopyridin-1-ium-2-carboxamide.

What is Sorafenib N-Oxide used for?

Sorafenib N-Oxide is supplied as a characterised reference material related to Sorafenib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Sorafenib N-Oxide can I order?

We supply Sorafenib N-Oxide in Reference Standard (91.55%) grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Sorafenib N-Oxide?

Yes. Every lot of Sorafenib N-Oxide is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Sorafenib N-Oxide be shipped internationally?

Yes. We export Sorafenib N-Oxide worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.