Sorafenib Tosylate

Name: Sorafenib Tosylate
Brand: Vaqora Chemicals
SKU: VQ-007762

About Sorafenib Tosylate

Sorafenib Tosylate (CAS 475207-59-1) is a high-purity reference standard of Sorafenib offered by Vaqora Chemicals. With the molecular formula C28H24ClF3N4O6S, it has a molar mass of 637.0 g/mol. Common synonyms include Sorafenib p-toluenesulfonate and 4-methylbenzenesulfonic acid.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. It carries the GHS signal word “Danger” with 5 hazard statements. Review the Safety Data Sheet before use.

Laboratories use this Sorafenib standard for identity and assay testing, system suitability checks and method validation supporting ANDA and DMF filings. It is used across pharmaceutical manufacturing and academic and industrial research.

We offer Sorafenib Tosylate in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide. This item is currently in stock for prompt dispatch.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Sorafenib

View every impurity, metabolite and intermediate we list for Sorafenib.

Sorafenib impurities

Specifications & identifiers

Chemical identifiers
Product name	Sorafenib Tosylate
Catalogue No.	VQ-007762
CAS Number	475207-59-1
Other CAS	284461-73-0
IUPAC name	4-[4-[[4-chloro-3-(trifluoromethyl)phenyl]carbamoylamino]phenoxy]-N-methylpyridine-2-carboxamide;4-methylbenzenesulfonic acid
Molecular formula	C₂₈H₂₄ClF₃N₄O₆S
Molecular weight	637 g/mol
Exact mass	636.1057
Grade	Reference Standard
HSN code	38229090
InChIKey	IVDHYUQIDRJSTI-UHFFFAOYSA-N
SMILES	CC1=CC=C(C=C1)S(=O)(=O)O.CNC(=O)C1=NC=CC(=C1)OC2=CC=C(C=C2)NC(=O)NC3=CC(=C(C=C3)Cl)C(F)(F)F
PubChem CID	406563

Physical properties
Physical form	Solid
H-bond donors / acceptors	4 / 10
TPSA	155 Å²
Synonyms	Sorafenib p-toluenesulfonate, 4-methylbenzenesulfonic acid, Sorafenib tosilate, BAY 43-9006 tosylate, Sorafenib (Tosylate), Sorafenib Hemitosylate, Sorafenib tosilate (JAN), Sorafenib (Nexavar), Sorafenib tosylate (USAN), Nexavar(R), 475207-59-1 (tosylate), C28H24ClF3N4O6S

Safety & hazard information (GHS)

Harmful / irritant

Health hazard

Signal word: Danger

Hazard statements

H302Harmful if swallowed
H332Harmful if inhaled
H360May damage fertility or the unborn child
H373May causes damage to organs through prolonged or repeated exposure
H412Harmful to aquatic life with long lasting effects

Precautionary statements: P203, P260, P261, P264, P270, P271, P273, P280, P301 + P317, P304 + P340, P317, P318, P319, P330, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Sorafenib Tosylate?

The CAS Registry Number of Sorafenib Tosylate is 475207-59-1. It is also known as Sorafenib p-toluenesulfonate, 4-methylbenzenesulfonic acid, Sorafenib tosilate.

What is the molecular formula and molecular weight of Sorafenib Tosylate?

Sorafenib Tosylate has the molecular formula C28H24ClF3N4O6S and a molecular weight of 637 g/mol.

What is Sorafenib Tosylate used for?

Sorafenib Tosylate is supplied as a characterised reference material related to Sorafenib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Sorafenib Tosylate can I order?

We supply Sorafenib Tosylate in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg, 500 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Sorafenib Tosylate?

Yes. Every lot of Sorafenib Tosylate is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Sorafenib Tosylate be shipped internationally?

Yes. Sorafenib Tosylate is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.