Trimetazidine

Name: Trimetazidine
Brand: Vaqora Chemicals
SKU: VQ-004112

About Trimetazidine

Listed under CAS 13171-25-0, Trimetazidine is a cardiovascular API available from Vaqora Chemicals (IP/BP/USP grade) with a typical assay of ≥98%. Its molecular formula is C14H24Cl2N2O3 and its molecular weight is 339.3 g/mol. Its systematic (IUPAC) name is 1-[(2,3,4-trimethoxyphenyl)methyl]piperazine. Dihydrochloride. Alternative names: Trimetazidine dihydrochloride and Trimetazidine hydrochloride.

The material typically appears as a white crystalline powder, slightly hygroscopic. Store sealed in a dry, well-ventilated location away from incompatible materials. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

As an active pharmaceutical ingredient within our cardiovascular and antihypertensive APIs range, it is offered in IP/BP/USP grade for formulation development, generic drug programmes and commercial manufacturing. Our customers for this product work in pharmaceutical manufacturing.

Vaqora Chemicals supplies Trimetazidine in 1 kg, 5 kg and 25 kg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Pharmaceutical formulation
Generic drug development

Industries

Related to Trimetazidine

View every impurity, metabolite and intermediate we list for Trimetazidine.

Trimetazidine impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Trimetazidine
Catalogue No.	VQ-004112
CAS Number	13171-25-0
IUPAC name	1-[(2,3,4-trimethoxyphenyl)methyl]piperazine;dihydrochloride
Molecular formula	C₁₄H₂₄Cl₂N₂O₃
Molecular weight	339.3 g/mol
Exact mass	338.1164
Grade	IP/BP/USP
Purity / assay	≥98%
HSN code	2933
InChIKey	VYFLPFGUVGMBEP-UHFFFAOYSA-N
SMILES	COC1=C(C(=C(C=C1)CN2CCNCC2)OC)OC.Cl.Cl
PubChem CID	83201

Physical properties
Physical form	Powder
Appearance	A white crystalline powder, slightly hygroscopic
H-bond donors / acceptors	3 / 5
TPSA	43 Å²
Synonyms	Trimetazidine dihydrochloride, 1-(2,3,4-Trimethoxybenzyl)piperazine dihydrochloride, Trimetazidine hydrochloride, Trimetazidine HCl, Trimetazidine di-hcl, Trimethazidine dihydrochloride, Dihydrochloride, Trimetazidine, 1-[(2,3,4-trimethoxyphenyl)methyl]piperazine dihydrochloride, Trimetazidine 2HCl, Trimetazidine (dihydrochloride), Piperazine, 1-[(2,3,4-trimethoxyphenyl)methyl]-, dihydrochloride, Preductal

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Trimetazidine?

The CAS Registry Number of Trimetazidine is 13171-25-0. It is also known as Trimetazidine dihydrochloride, 1-(2,3,4-Trimethoxybenzyl)piperazine dihydrochloride, Trimetazidine hydrochloride.

What is the molecular formula and molecular weight of Trimetazidine?

Trimetazidine has the molecular formula C14H24Cl2N2O3 and a molecular weight of 339.3 g/mol.

What is Trimetazidine used for?

Trimetazidine is supplied as a characterised reference material related to Trimetazidine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Trimetazidine can I order?

We supply Trimetazidine in IP/BP/USP (≥98%) grade, in 1 kg, 5 kg, 25 kg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Trimetazidine?

Yes. Every lot of Trimetazidine is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Trimetazidine be shipped internationally?

Yes. Trimetazidine is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.