Verapamil Hydrochloride

Name: Verapamil Hydrochloride
Brand: Vaqora Chemicals
SKU: VQ-004114

About Verapamil Hydrochloride

Listed under CAS 52-53-9, Verapamil Hydrochloride is a cardiovascular API available from Vaqora Chemicals in IP/BP/USP grade. With the molecular formula C27H38N2O4, it has a molar mass of 454.6 g/mol. Systematically, it is named 2-(3,4-dimethoxyphenyl)-5-[2-(3,4-dimethoxyphenyl)ethyl-methylamino]-2-propan-2-ylpentanenitrile. It is also known as Cardibeltin or Isoptine.

It is supplied as a powder. Keep the container tightly sealed and store it in a cool, dry area. Under GHS it is labelled “Danger”, so handle it with suitable PPE and consult the SDS.

As an active pharmaceutical ingredient within our cardiovascular and antihypertensive APIs range, it is offered in IP/BP/USP grade for formulation development, generic drug programmes and commercial manufacturing. Our customers for this product work in pharmaceutical manufacturing.

We offer Verapamil Hydrochloride in 1 kg, 5 kg and 25 kg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Pharmaceutical formulation
Generic drug development

Industries

Related to Verapamil

View every impurity, metabolite and intermediate we list for Verapamil.

Verapamil impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Verapamil Hydrochloride
Catalogue No.	VQ-004114
CAS Number	52-53-9
IUPAC name	2-(3,4-dimethoxyphenyl)-5-[2-(3,4-dimethoxyphenyl)ethyl-methylamino]-2-propan-2-ylpentanenitrile
Molecular formula	C₂₇H₃₈N₂O₄
Molecular weight	454.6 g/mol
Exact mass	454.2832
Grade	IP/BP/USP
HSN code	2933
InChIKey	SGTNSNPWRIOYBX-UHFFFAOYSA-N
SMILES	CC(C)C(CCCN(C)CCC1=CC(=C(C=C1)OC)OC)(C#N)C2=CC(=C(C=C2)OC)OC
PubChem CID	2520

Physical properties
Physical form	Powder
LogP (XLogP3)	3.8
H-bond donors / acceptors	0 / 6
TPSA	64 Å²
Synonyms	Cardibeltin, Isoptine, dl-Verapamil, Novo-Veramil, r,s-verapamil, Apo-Verap, Nu-Verap, 5-((3,4-Dimethoxyphenethyl)methylamino)-2-(3,4-dimethoxyphenyl)-2-isopropylvaleronitrile, Verapamil slow release, Cardiabeltin, Durasoptin, Hexasoptin

Safety & hazard information (GHS)

Health hazard

Signal word: Danger

Hazard statements

H301Toxic if swallowed
H311Toxic in contact with skin
H331Toxic if inhaled

Precautionary statements: P261, P262, P264, P270, P271, P280, P301 + P316, P302 + P352, P304 + P340, P316, P321, P330, P361 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Other grades of CAS 52-53-9

Reference Standard

Verapamil

CAS: 52-53-9
Formula: C₂₇H₃₈N₂O₄
MW: 454.6 g/mol

VQ-007843

Frequently asked questions

What is the CAS number of Verapamil Hydrochloride?

The CAS Registry Number of Verapamil Hydrochloride is 52-53-9. It is also known as Cardibeltin, Isoptine, dl-Verapamil.

What is the molecular formula and molecular weight of Verapamil Hydrochloride?

Verapamil Hydrochloride has the molecular formula C27H38N2O4 and a molecular weight of 454.6 g/mol. Its IUPAC name is 2-(3,4-dimethoxyphenyl)-5-[2-(3,4-dimethoxyphenyl)ethyl-methylamino]-2-propan-2-ylpentanenitrile.

What is Verapamil Hydrochloride used for?

Verapamil Hydrochloride is supplied as a characterised reference material related to Verapamil. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Verapamil Hydrochloride can I order?

We supply Verapamil Hydrochloride in IP/BP/USP grade, in 1 kg, 5 kg, 25 kg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Verapamil Hydrochloride?

Yes. Every lot of Verapamil Hydrochloride is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Verapamil Hydrochloride be shipped internationally?

Yes. Verapamil Hydrochloride is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.