(R)-Ambrisentan

Name: (R)-Ambrisentan
Brand: Vaqora Chemicals
SKU: VQ-020779

About (R)-Ambrisentan

Listed under CAS 1007358-76-0, (R)-Ambrisentan is a high-purity reference standard of Ambrisentan available from Vaqora Chemicals. The compound has the formula C22H22N2O4, corresponding to a molecular weight of 378.4 g/mol. Systematically, it is named (2R)-2-(4,6-dimethylpyrimidin-2-yl)oxy-3-methoxy-3,3-diphenylpropanoic acid. Alternative names: Ambrisentan (R)-Isomer and Ambrisentan R isomer.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Good laboratory practice and suitable PPE are recommended during handling.

Laboratories use this Ambrisentan standard for identity and assay testing, system suitability checks and method validation supporting ANDA and DMF filings. It is used across pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Ambrisentan

View every impurity, metabolite and intermediate we list for Ambrisentan.

Ambrisentan impurities

Specifications & identifiers

Chemical identifiers
Product name	(R)-Ambrisentan
Catalogue No.	VQ-020779
CAS Number	1007358-76-0
IUPAC name	(2R)-2-(4,6-dimethylpyrimidin-2-yl)oxy-3-methoxy-3,3-diphenylpropanoic acid
Molecular formula	C₂₂H₂₂N₂O₄
Molecular weight	378.4 g/mol
Exact mass	378.158
Grade	Reference Standard
HSN code	38229090
InChIKey	OUJTZYPIHDYQMC-IBGZPJMESA-N
SMILES	CC1=CC(=NC(=N1)O[C@@H](C(=O)O)C(C2=CC=CC=C2)(C3=CC=CC=C3)OC)C
PubChem CID	7045769

Physical properties
Physical form	Solid
LogP (XLogP3)	3.8
H-bond donors / acceptors	1 / 6
TPSA	81.5 Å²
Synonyms	Ambrisentan (R)-Isomer, Ambrisentan R isomer, Ambrisentan, (R)-, Ambrisentan, (-)-, (R)-2-((4,6-Dimethylpyrimidin-2-yl)oxy)-3-methoxy-3,3-diphenylpropanoic acid

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of (R)-Ambrisentan?

The CAS Registry Number of (R)-Ambrisentan is 1007358-76-0. It is also known as Ambrisentan (R)-Isomer, Ambrisentan R isomer, Ambrisentan, (R)-.

What is the molecular formula and molecular weight of (R)-Ambrisentan?

(R)-Ambrisentan has the molecular formula C22H22N2O4 and a molecular weight of 378.4 g/mol. Its IUPAC name is (2R)-2-(4,6-dimethylpyrimidin-2-yl)oxy-3-methoxy-3,3-diphenylpropanoic acid.

What is (R)-Ambrisentan used for?

(R)-Ambrisentan is supplied as a characterised reference material related to Ambrisentan. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of (R)-Ambrisentan can I order?

We supply (R)-Ambrisentan in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with (R)-Ambrisentan?

Yes. Every lot of (R)-Ambrisentan is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can (R)-Ambrisentan be shipped internationally?

Yes. We export (R)-Ambrisentan worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.