2,5-Dioxopyrrolidine Sacubitril

Name: 2,5-Dioxopyrrolidine Sacubitril
Brand: Vaqora Chemicals
SKU: VQ-012894

About 2,5-Dioxopyrrolidine Sacubitril

Vaqora Chemicals supplies 2,5-Dioxopyrrolidine Sacubitril, a process intermediate or related compound of Sacubitril registered under CAS number 1038924-97-8 with a typical assay of 99%. With the molecular formula C24H27NO4, it has a molar mass of 393.5 g/mol. Systematically, it is named ethyl (2R,4S)-4-(2,5-dioxopyrrolidin-1-yl)-2-methyl-5-(4-phenylphenyl)pentanoate. Alternative names: LCZ-696-006-RS.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Handle it with standard laboratory precautions and appropriate personal protective equipment.

Process chemists and analysts use it when developing synthetic routes to Sacubitril, tracking process-related impurities and validating analytical methods. It is used across pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, 2,5-Dioxopyrrolidine Sacubitril is dispatched with a Certificate of Analysis (COA) to destinations worldwide. Stock is available for quick dispatch.

Typical applications

API route development
Impurity fate & purge studies
Analytical method development

Industries

Related to Sacubitril

View every impurity, metabolite and intermediate we list for Sacubitril.

Sacubitril impurities

Specifications & identifiers

Chemical identifiers
Product name	2,5-Dioxopyrrolidine Sacubitril
Catalogue No.	VQ-012894
CAS Number	1038924-97-8
IUPAC name	ethyl (2R,4S)-4-(2,5-dioxopyrrolidin-1-yl)-2-methyl-5-(4-phenylphenyl)pentanoate
Molecular formula	C₂₄H₂₇NO₄
Molecular weight	393.5 g/mol
Exact mass	393.194
Grade	Reference Standard
Purity / assay	99%
HSN code	2933
InChIKey	UXCICAHPGZDADX-UTKZUKDTSA-N
SMILES	CCOC(=O)[C@H](C)C[C@@H](CC1=CC=C(C=C1)C2=CC=CC=C2)N3C(=O)CCC3=O
PubChem CID	66739220

Physical properties
Physical form	Solid
LogP (XLogP3)	3.9
H-bond donors / acceptors	0 / 4
TPSA	63.7 Å²
Synonyms	(2R,4S)-5-(Biphenyl-4-yl)-4-(2,5-dioxopyrrolidin-1-yl)-2-methylpentanoic Acid Ethyl Ester, Ethyl (2R,4S)-5-([1,1'-biphenyl]-4-yl)-4-(2,5-dioxopyrrolidin-1-yl)-2-methylpentanoate, Ethyl (αR,γS)-γ-([1,1′-biphenyl]-4-ylmethyl)-α-methyl-2,5-dioxo-1-pyrrolidinebutanoate, (2R,4S)-ethyl 5-([1,1'-biphenyl]-4-yl)-4-(2,5-dioxopyrrolidin-1-yl)-2-methylpentanoate, 2,5-Dioxopyrrolidine Sacubitril, (2R,4S)-5-Biphenyl-4-yl-4-(2,5-dioxopyrrolidin-1-yl)-2-methylpentanoic acid ethyl ester, LCZ-696-006-RS, ethyl(2R,4S)-5-([1,1'-biphenyl]-4-yl)-4-(2,5-dioxopyrrolidin-1-yl)-2-methylpentanoate

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 2,5-Dioxopyrrolidine Sacubitril?

The CAS Registry Number of 2,5-Dioxopyrrolidine Sacubitril is 1038924-97-8. It is also known as (2R,4S)-5-(Biphenyl-4-yl)-4-(2,5-dioxopyrrolidin-1-yl)-2-methylpentanoic Acid Ethyl Ester, Ethyl (2R,4S)-5-([1,1'-biphenyl]-4-yl)-4-(2,5-dioxopyrrolidin-1-yl)-2-methylpentanoate, Ethyl (αR,γS)-γ-([1,1′-biphenyl]-4-ylmethyl)-α-methyl-2,5-dioxo-1-pyrrolidinebutanoate.

What is the molecular formula and molecular weight of 2,5-Dioxopyrrolidine Sacubitril?

2,5-Dioxopyrrolidine Sacubitril has the molecular formula C24H27NO4 and a molecular weight of 393.5 g/mol. Its IUPAC name is ethyl (2R,4S)-4-(2,5-dioxopyrrolidin-1-yl)-2-methyl-5-(4-phenylphenyl)pentanoate.

What is 2,5-Dioxopyrrolidine Sacubitril used for?

2,5-Dioxopyrrolidine Sacubitril is supplied as a characterised reference material related to Sacubitril. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 2,5-Dioxopyrrolidine Sacubitril can I order?

We supply 2,5-Dioxopyrrolidine Sacubitril in Reference Standard (99%) grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 2,5-Dioxopyrrolidine Sacubitril?

Yes. Every lot of 2,5-Dioxopyrrolidine Sacubitril is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 2,5-Dioxopyrrolidine Sacubitril be shipped internationally?

Yes. We export 2,5-Dioxopyrrolidine Sacubitril worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.