Everolimus EP Impurity B

About Everolimus EP Impurity B

Everolimus EP Impurity B is a pharmacopeial impurity of Everolimus carrying the CAS registry number 1062122-63-7. The compound has the formula C53H83NO14, corresponding to a molecular weight of 958.2 g/mol. Common synonyms include Everolimus - Impurity B and Everolimus-19-ene open ring.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Good laboratory practice and suitable PPE are recommended during handling.

This Everolimus impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. It is used across pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Everolimus EP Impurity B is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Everolimus

View every impurity, metabolite and intermediate we list for Everolimus.

Everolimus impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Everolimus EP Impurity B
Catalogue No.	VQ-030641
CAS Number	1062122-63-7
IUPAC name	(2S)-1-[2-[(2R,3R,6S)-2-hydroxy-6-[(2S,3E,5E,7E,9S,11R,13R,14R,15E,17R,19E,21R)-14-hydroxy-22-[(1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl]-2,13-dimethoxy-3,9,11,15,17,21-hexamethyl-12,18-dioxodocosa-3,5,7,15,19-pentaenyl]-3-methyloxan-2-yl]-2-oxoacetyl]piperidine-2-carboxylic acid
Molecular formula	C₅₃H₈₃NO₁₄
Molecular weight	958.2 g/mol
Exact mass	957.5814
Grade	Reference Standard
HSN code	38229090
InChIKey	PRSJHEVLVQFMHJ-FRLQEACCSA-N
SMILES	C[C@@H]1CC[C@H](O[C@]1(C(=O)C(=O)N2CCCC[C@H]2C(=O)O)O)C[C@@H](/C(=C/C=C/C=C/[C@@H](C)C[C@@H](C)C(=O)[C@@H]([C@@H](/C(=C/[C@@H](C)C(=O)/C=C/[C@H](C)C[C@@H]3CC[C@H]([C@@H](C3)OC)OCCO)/C)O)OC)/C)OC
PubChem CID	139025362

Physical properties
Physical form	Solid
LogP (XLogP3)	7.4
H-bond donors / acceptors	4 / 14
TPSA	216 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Everolimus EP Impurity B?

The CAS Registry Number of Everolimus EP Impurity B is 1062122-63-7. It is also known as Everolimus - Impurity B, Everolimus-19-ene open ring, (19E/Z)-seco-[4-O-(2-Hydroxyethyl)]Rapamycin.

What is the molecular formula and molecular weight of Everolimus EP Impurity B?

Everolimus EP Impurity B has the molecular formula C53H83NO14 and a molecular weight of 958.2 g/mol.

What is Everolimus EP Impurity B used for?

Everolimus EP Impurity B is supplied as a characterised reference material related to Everolimus. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Everolimus EP Impurity B can I order?

We supply Everolimus EP Impurity B in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Everolimus EP Impurity B?

Yes. Every lot of Everolimus EP Impurity B is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Everolimus EP Impurity B be shipped internationally?

Yes. We export Everolimus EP Impurity B worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.