Nintedanib acetyl impurity

About Nintedanib acetyl impurity

Nintedanib acetyl impurity is an impurity of Nintedanib carrying the CAS registry number 1139458-48-2. Its molecular formula is C26H23N3O4 and its molecular weight is 441.5 g/mol. Its systematic (IUPAC) name is methyl 3-[N-[4-[acetyl(methyl)amino]phenyl]-C-phenylcarbonimidoyl]-2-hydroxy-1H-indole-6-carboxylate. Alternative names: Nintedanib N-Acetyl Aniline Analog and Nintedanib N-Acetyl Analog.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Good laboratory practice and suitable PPE are recommended during handling.

This Nintedanib impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Nintedanib acetyl impurity is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Nintedanib

View every impurity, metabolite and intermediate we list for Nintedanib.

Nintedanib impurities

Specifications & identifiers

Chemical identifiers
Product name	Nintedanib acetyl impurity
Catalogue No.	VQ-028841
CAS Number	1139458-48-2
IUPAC name	methyl 3-[N-[4-[acetyl(methyl)amino]phenyl]-C-phenylcarbonimidoyl]-2-hydroxy-1H-indole-6-carboxylate
Molecular formula	C₂₆H₂₃N₃O₄
Molecular weight	441.5 g/mol
Exact mass	441.1689
Grade	Reference Standard
HSN code	38229090
InChIKey	VNCLRRPVWWQUSV-UHFFFAOYSA-N
SMILES	CC(=O)N(C)C1=CC=C(C=C1)N=C(C2=CC=CC=C2)C3=C(NC4=C3C=CC(=C4)C(=O)OC)O
PubChem CID	135837818

Physical properties
Physical form	Solid
LogP (XLogP3)	4.4
H-bond donors / acceptors	2 / 5
TPSA	95 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Nintedanib acetyl impurity?

The CAS Registry Number of Nintedanib acetyl impurity is 1139458-48-2. It is also known as Nintedanib N-Acetyl Aniline Analog, Nintedanib N-Acetyl Analog, Nintedanib Impurity N8.

What is the molecular formula and molecular weight of Nintedanib acetyl impurity?

Nintedanib acetyl impurity has the molecular formula C26H23N3O4 and a molecular weight of 441.5 g/mol. Its IUPAC name is methyl 3-[N-[4-[acetyl(methyl)amino]phenyl]-C-phenylcarbonimidoyl]-2-hydroxy-1H-indole-6-carboxylate.

What is Nintedanib acetyl impurity used for?

Nintedanib acetyl impurity is supplied as a characterised reference material related to Nintedanib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Nintedanib acetyl impurity can I order?

We supply Nintedanib acetyl impurity in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Nintedanib acetyl impurity?

Yes. Every lot of Nintedanib acetyl impurity is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Nintedanib acetyl impurity be shipped internationally?

Yes. We export Nintedanib acetyl impurity worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.