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VAQORAN-(4-((3-Chloro-4-(pyridin-2-ylmethoxy)phenyl)amino)-3-cyano-7-ethoxyquinolin-6-yl)formamide
Synonyms: N-[4-[3-chloro-4-(2-pyridylmethoxy)anilino]-3-cyano-7-ethoxy-6-quinolyl]formamide
CAS No.1144516-20-0
FormulaC25H20ClN5O3
Mol. weight473.90
Catalogue No.VQ-028936
PurityReference Standard
HSN38229090
N-(4-((3-Chloro-4-(pyridin-2-ylmethoxy)phenyl)amino)-3-cyano-7-ethoxyquinolin-6-yl)formamide (CAS 1144516-20-0) – Neratinib impurity standard. COA included.
Pack sizesPrice on quotation · bulk available
10 mg
25 mg
50 mg
100 mg
Bulk / custom pack · kg to MT
Enquire Batch COA with every lot
16-section GHS SDS
Export to 120+ countries
DG-compliant packing
About N-(4-((3-Chloro-4-(pyridin-2-ylmethoxy)phenyl)amino)-3-cyano-7-ethoxyquinolin-6-yl)formamide
N-(4-((3-Chloro-4-(pyridin-2-ylmethoxy)phenyl)amino)-3-cyano-7-ethoxyquinolin-6-yl)formamide is an impurity of Neratinib carrying the CAS registry number 1144516-20-0. Its molecular formula is C25H20ClN5O3 and its molecular weight is 473.9 g/mol. The IUPAC name is N-[4-[3-chloro-4-(pyridin-2-ylmethoxy)anilino]-3-cyano-7-ethoxyquinolin-6-yl]formamide.
The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Handle it with standard laboratory precautions and appropriate personal protective equipment.
Pharmaceutical QC and development laboratories use this impurity standard of Neratinib to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.
Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.
Typical applications
- Analytical method development
- Method validation (AMV)
- QC release testing
- ANDA / DMF filings
Industries
Related to Neratinib
View every impurity, metabolite and intermediate we list for Neratinib.
Neratinib impuritiesSpecifications & identifiers
| Product name | N-(4-((3-Chloro-4-(pyridin-2-ylmethoxy)phenyl)amino)-3-cyano-7-ethoxyquinolin-6-yl)formamide |
|---|---|
| Catalogue No. | VQ-028936 |
| CAS Number | 1144516-20-0 |
| IUPAC name | N-[4-[3-chloro-4-(pyridin-2-ylmethoxy)anilino]-3-cyano-7-ethoxyquinolin-6-yl]formamide |
| Molecular formula | C25H20ClN5O3 |
| Molecular weight | 473.9 g/mol |
| Exact mass | 473.1255 |
| Grade | Reference Standard |
| HSN code | 38229090 |
| InChIKey | DHEYZLWFAKSQIZ-UHFFFAOYSA-N |
| SMILES | CCOC1=C(C=C2C(=C1)N=CC(=C2NC3=CC(=C(C=C3)OCC4=CC=CC=N4)Cl)C#N)NC=O |
| PubChem CID | 57775610 |
| Physical form | Solid |
|---|---|
| LogP (XLogP3) | 4.6 |
| H-bond donors / acceptors | 2 / 7 |
| TPSA | 109 Ų |
Documents
Frequently asked questions
What is the CAS number of N-(4-((3-Chloro-4-(pyridin-2-ylmethoxy)phenyl)amino)-3-cyano-7-ethoxyquinolin-6-yl)formamide?
The CAS Registry Number of N-(4-((3-Chloro-4-(pyridin-2-ylmethoxy)phenyl)amino)-3-cyano-7-ethoxyquinolin-6-yl)formamide is 1144516-20-0. It is also known as N-[4-[3-chloro-4-(2-pyridylmethoxy)anilino]-3-cyano-7-ethoxy-6-quinolyl]formamide.
What is the molecular formula and molecular weight of N-(4-((3-Chloro-4-(pyridin-2-ylmethoxy)phenyl)amino)-3-cyano-7-ethoxyquinolin-6-yl)formamide?
N-(4-((3-Chloro-4-(pyridin-2-ylmethoxy)phenyl)amino)-3-cyano-7-ethoxyquinolin-6-yl)formamide has the molecular formula C25H20ClN5O3 and a molecular weight of 473.9 g/mol. Its IUPAC name is N-[4-[3-chloro-4-(pyridin-2-ylmethoxy)anilino]-3-cyano-7-ethoxyquinolin-6-yl]formamide.
What is N-(4-((3-Chloro-4-(pyridin-2-ylmethoxy)phenyl)amino)-3-cyano-7-ethoxyquinolin-6-yl)formamide used for?
N-(4-((3-Chloro-4-(pyridin-2-ylmethoxy)phenyl)amino)-3-cyano-7-ethoxyquinolin-6-yl)formamide is supplied as a characterised reference material related to Neratinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.
Which grade and pack sizes of N-(4-((3-Chloro-4-(pyridin-2-ylmethoxy)phenyl)amino)-3-cyano-7-ethoxyquinolin-6-yl)formamide can I order?
We supply N-(4-((3-Chloro-4-(pyridin-2-ylmethoxy)phenyl)amino)-3-cyano-7-ethoxyquinolin-6-yl)formamide in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.
Do you provide a COA and SDS with N-(4-((3-Chloro-4-(pyridin-2-ylmethoxy)phenyl)amino)-3-cyano-7-ethoxyquinolin-6-yl)formamide?
Yes. Every lot of N-(4-((3-Chloro-4-(pyridin-2-ylmethoxy)phenyl)amino)-3-cyano-7-ethoxyquinolin-6-yl)formamide is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.
Can N-(4-((3-Chloro-4-(pyridin-2-ylmethoxy)phenyl)amino)-3-cyano-7-ethoxyquinolin-6-yl)formamide be shipped internationally?
Yes. We export N-(4-((3-Chloro-4-(pyridin-2-ylmethoxy)phenyl)amino)-3-cyano-7-ethoxyquinolin-6-yl)formamide worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.
Enquire about N-(4-((3-Chloro-4-(pyridin-2-ylmethoxy)phenyl)amino)-3-cyano-7-ethoxyquinolin-6-yl)formamide
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