Loxapine D8

About Loxapine D8

Loxapine D8 is a stable isotope labelled analogue related to Loxapine carrying the CAS registry number 1189455-63-7. With the molecular formula C18H18ClN3O, it has a molar mass of 335.9 g/mol. Its systematic (IUPAC) name is 8-chloro-6-(2,2,3,3,5,5,6,6-octadeuterio-4-methylpiperazin-1-yl)benzo[b][1,4]benzoxazepine.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Under GHS it is labelled “Danger”, so handle it with suitable PPE and consult the SDS.

Its mass shift relative to the unlabelled analyte makes it a dependable internal standard for LC-MS/MS assays, improving accuracy in bioanalysis, therapeutic drug monitoring and method validation. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Loxapine D8 is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

LC-MS/MS internal standard
Bioanalytical quantitation
Pharmacokinetic studies

Industries

Related to Loxapine

View every impurity, metabolite and intermediate we list for Loxapine.

Loxapine impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Loxapine D8
Catalogue No.	VQ-048968
CAS Number	1189455-63-7
IUPAC name	8-chloro-6-(2,2,3,3,5,5,6,6-octadeuterio-4-methylpiperazin-1-yl)benzo[b][1,4]benzoxazepine
Molecular formula	C₁₈H₁₈ClN₃O
Molecular weight	335.9 g/mol
Exact mass	335.1641
Grade	Reference Standard
HSN code	38229090
InChIKey	XJGVXQDUIWGIRW-JNJBWJDISA-N
SMILES	[2H]C1(C(N(C(C(N1C)([2H])[2H])([2H])[2H])C2=NC3=CC=CC=C3OC4=C2C=C(C=C4)Cl)([2H])[2H])[2H]
PubChem CID	46782087

Physical properties
Physical form	Solid
LogP (XLogP3)	3.1
H-bond donors / acceptors	0 / 3
TPSA	28.1 Å²

Safety & hazard information (GHS)

Toxic

Signal word: Danger

Hazard statements

H301Toxic if swallowed

Precautionary statements: P264, P270, P301 + P316, P321, P330, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Loxapine D8?

The CAS Registry Number of Loxapine D8 is 1189455-63-7. It is also known as 2-Chloro-11-(4-methyl-1-piperazinyl-D8)-dibenz(b,f)(1,4)oxazepine, 2-Chloro-11-(4-methyl-1-piperazinyl-D8)-dibenz[b,f][1,4]oxazepine, 2-chloro-11-(4-methylpiperazin-1-yl-2,2,3,3,5,5,6,6-d8)dibenzo[b,f][1,4]oxazepine.

What is the molecular formula and molecular weight of Loxapine D8?

Loxapine D8 has the molecular formula C18H18ClN3O and a molecular weight of 335.9 g/mol. Its IUPAC name is 8-chloro-6-(2,2,3,3,5,5,6,6-octadeuterio-4-methylpiperazin-1-yl)benzo[b][1,4]benzoxazepine.

What is Loxapine D8 used for?

Loxapine D8 is supplied as a characterised reference material related to Loxapine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Loxapine D8 can I order?

We supply Loxapine D8 in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Loxapine D8?

Yes. Every lot of Loxapine D8 is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Loxapine D8 be shipped internationally?

Yes. Loxapine D8 is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.