1'-Hydroxy Midazolam-13C3

About 1'-Hydroxy Midazolam-13C3

1'-Hydroxy Midazolam-13C3 is a stable isotope labelled analogue related to Midazolam carrying the CAS registry number 1189677-14-2. Its molecular formula is C18H13ClFN3O and its molecular weight is 344.74 g/mol. Systematically, it is named [8-chloro-6-(2-fluorophenyl)-4H-(2,5-13C2)imidazolo[1,5-a][1,4]benzodiazepin-1-yl](113C)methanol.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. It carries the GHS signal word “Warning” with 2 hazard statements. Review the Safety Data Sheet before use.

This isotope-labelled compound is used as an internal standard for LC-MS and LC-MS/MS quantitation of Midazolam and related analytes in bioanalytical, pharmacokinetic and impurity studies. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, 1'-Hydroxy Midazolam-13C3 is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

LC-MS/MS internal standard
Bioanalytical quantitation
Pharmacokinetic studies

Industries

Related to Midazolam

View every impurity, metabolite and intermediate we list for Midazolam.

Midazolam impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	1'-Hydroxy Midazolam-13C3
Catalogue No.	VQ-044870
CAS Number	1189677-14-2
IUPAC name	[8-chloro-6-(2-fluorophenyl)-4H-(2,5-13C2)imidazolo[1,5-a][1,4]benzodiazepin-1-yl](113C)methanol
Molecular formula	C₁₈H₁₃ClFN₃O
Molecular weight	344.74 g/mol
Exact mass	344.0832
Grade	Reference Standard
HSN code	38229090
InChIKey	QHSMEGADRFZVNE-BHKULXQMSA-N
SMILES	C1[13C]2=CN=[13C](N2C3=C(C=C(C=C3)Cl)C(=N1)C4=CC=CC=C4F)[13CH2]O
PubChem CID	45039480

Physical properties
Physical form	Solid
LogP (XLogP3)	2.7
H-bond donors / acceptors	1 / 4
TPSA	50.4 Å²

Safety & hazard information (GHS)

Harmful / irritant

Environmental hazard

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H400Very toxic to aquatic life

Precautionary statements: P264, P270, P273, P301 + P317, P330, P391, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 1'-Hydroxy Midazolam-13C3?

The CAS Registry Number of 1'-Hydroxy Midazolam-13C3 is 1189677-14-2.

What is the molecular formula and molecular weight of 1'-Hydroxy Midazolam-13C3?

1'-Hydroxy Midazolam-13C3 has the molecular formula C18H13ClFN3O and a molecular weight of 344.74 g/mol. Its IUPAC name is [8-chloro-6-(2-fluorophenyl)-4H-(2,5-13C2)imidazolo[1,5-a][1,4]benzodiazepin-1-yl](113C)methanol.

What is 1'-Hydroxy Midazolam-13C3 used for?

1'-Hydroxy Midazolam-13C3 is supplied as a characterised reference material related to Midazolam. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 1'-Hydroxy Midazolam-13C3 can I order?

We supply 1'-Hydroxy Midazolam-13C3 in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 1'-Hydroxy Midazolam-13C3?

Yes. Every lot of 1'-Hydroxy Midazolam-13C3 is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 1'-Hydroxy Midazolam-13C3 be shipped internationally?

Yes. 1'-Hydroxy Midazolam-13C3 is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.