Dabrafenib Amine Impurity

Name: Dabrafenib Amine Impurity
Brand: Vaqora Chemicals
SKU: VQ-029992

About Dabrafenib Amine Impurity

Dabrafenib Amine Impurity (CAS 1195769-01-7) is an impurity of Dabrafenib offered by Vaqora Chemicals. With the molecular formula C17H18FN5S, it has a molar mass of 343.4 g/mol. The IUPAC name is 4-[4-(3-amino-2-fluorophenyl)-2-tert-butyl-1,3-thiazol-5-yl]pyrimidin-2-amine. Common synonyms include Dabrafenib Impurity 46 and Dabrafenib Impurity 47.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

As a characterised impurity of Dabrafenib, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Dabrafenib

View every impurity, metabolite and intermediate we list for Dabrafenib.

Dabrafenib impurities

Specifications & identifiers

Chemical identifiers
Product name	Dabrafenib Amine Impurity
Catalogue No.	VQ-029992
CAS Number	1195769-01-7
IUPAC name	4-[4-(3-amino-2-fluorophenyl)-2-tert-butyl-1,3-thiazol-5-yl]pyrimidin-2-amine
Molecular formula	C₁₇H₁₈FN₅S
Molecular weight	343.4 g/mol
Exact mass	343.1267
Grade	Reference Standard
HSN code	38229090
InChIKey	OXKPDDILTMNBMA-UHFFFAOYSA-N
SMILES	CC(C)(C)C1=NC(=C(S1)C2=NC(=NC=C2)N)C3=C(C(=CC=C3)N)F
PubChem CID	57989709

Physical properties
Physical form	Solid
LogP (XLogP3)	3.4
H-bond donors / acceptors	2 / 7
TPSA	119 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Dabrafenib Amine Impurity?

The CAS Registry Number of Dabrafenib Amine Impurity is 1195769-01-7. It is also known as Dabrafenib Impurity 46, Dabrafenib Impurity 47, 4-(4-(3-amino-2-fluorophenyl)-2-(tert-butyl)thiazol-5-yl)pyrimidin-2-amine.

What is the molecular formula and molecular weight of Dabrafenib Amine Impurity?

Dabrafenib Amine Impurity has the molecular formula C17H18FN5S and a molecular weight of 343.4 g/mol. Its IUPAC name is 4-[4-(3-amino-2-fluorophenyl)-2-tert-butyl-1,3-thiazol-5-yl]pyrimidin-2-amine.

What is Dabrafenib Amine Impurity used for?

Dabrafenib Amine Impurity is supplied as a characterised reference material related to Dabrafenib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Dabrafenib Amine Impurity can I order?

We supply Dabrafenib Amine Impurity in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Dabrafenib Amine Impurity?

Yes. Every lot of Dabrafenib Amine Impurity is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Dabrafenib Amine Impurity be shipped internationally?

Yes. We export Dabrafenib Amine Impurity worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.