10-Acetyl-10H-phenothiazine 5-oxide

Name: 10-Acetyl-10H-phenothiazine 5-oxide
Brand: Vaqora Chemicals
SKU: VQ-041703

About 10-Acetyl-10H-phenothiazine 5-oxide

Vaqora Chemicals supplies 10-Acetyl-10H-phenothiazine 5-oxide, an impurity of Promethazine registered under CAS number 1217-37-4. Its molecular formula is C14H11NO2S and its molecular weight is 257.31 g/mol. Its systematic (IUPAC) name is 1-(5-oxophenothiazin-10-yl)ethanone. Alternative names: Phenothiazine, 10-acetyl-, 5-oxide and 10H-Phenothiazine, 10-acetyl-, 5-oxide.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Handle it with standard laboratory precautions and appropriate personal protective equipment.

Pharmaceutical QC and development laboratories use this impurity standard of Promethazine to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. It is used across pharmaceutical manufacturing and academic and industrial research.

We offer 10-Acetyl-10H-phenothiazine 5-oxide in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Promethazine

View every impurity, metabolite and intermediate we list for Promethazine.

Promethazine impurities

Specifications & identifiers

Chemical identifiers
Product name	10-Acetyl-10H-phenothiazine 5-oxide
Catalogue No.	VQ-041703
CAS Number	1217-37-4
IUPAC name	1-(5-oxophenothiazin-10-yl)ethanone
Molecular formula	C₁₄H₁₁NO₂S
Molecular weight	257.31 g/mol
Exact mass	257.051
Grade	Reference Standard
HSN code	38229090
InChIKey	SZLYHEJOJMRRFR-UHFFFAOYSA-N
SMILES	CC(=O)N1C2=CC=CC=C2S(=O)C3=CC=CC=C31
PubChem CID	219971

Physical properties
Physical form	Solid
LogP (XLogP3)	1.7
H-bond donors / acceptors	0 / 3
TPSA	67.3 Å²
Synonyms	Phenothiazine, 10-acetyl-, 5-oxide, 10H-Phenothiazine, 10-acetyl-, 5-oxide, 10-acetylphenothiazine S-oxide, 1-(5-oxido-10H-phenothiazin-10-yl)ethanone, 10-Acetyl-5lambda~4~-phenothiazin-5(10H)-one

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 10-Acetyl-10H-phenothiazine 5-oxide?

The CAS Registry Number of 10-Acetyl-10H-phenothiazine 5-oxide is 1217-37-4. It is also known as Phenothiazine, 10-acetyl-, 5-oxide, 10H-Phenothiazine, 10-acetyl-, 5-oxide, 10-acetylphenothiazine S-oxide.

What is the molecular formula and molecular weight of 10-Acetyl-10H-phenothiazine 5-oxide?

10-Acetyl-10H-phenothiazine 5-oxide has the molecular formula C14H11NO2S and a molecular weight of 257.31 g/mol. Its IUPAC name is 1-(5-oxophenothiazin-10-yl)ethanone.

What is 10-Acetyl-10H-phenothiazine 5-oxide used for?

10-Acetyl-10H-phenothiazine 5-oxide is supplied as a characterised reference material related to Promethazine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 10-Acetyl-10H-phenothiazine 5-oxide can I order?

We supply 10-Acetyl-10H-phenothiazine 5-oxide in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 10-Acetyl-10H-phenothiazine 5-oxide?

Yes. Every lot of 10-Acetyl-10H-phenothiazine 5-oxide is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 10-Acetyl-10H-phenothiazine 5-oxide be shipped internationally?

Yes. We export 10-Acetyl-10H-phenothiazine 5-oxide worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.