Promethazine N-Oxide

Name: Promethazine N-Oxide
Brand: Vaqora Chemicals
SKU: VQ-033350

About Promethazine N-Oxide

Promethazine N-Oxide is a metabolite or degradation product of Promethazine carrying the CAS registry number 81480-39-9. With the molecular formula C17H20N2OS, it has a molar mass of 300.4 g/mol. Its systematic (IUPAC) name is N,N-dimethyl-1-phenothiazin-10-ylpropan-2-amine oxide.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Good laboratory practice and suitable PPE are recommended during handling.

Analytical teams use this compound to identify metabolites and degradants of Promethazine, to validate stability-indicating methods (AMV) and to support QC and regulatory filings. It is used across pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Promethazine N-Oxide is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Promethazine

View every impurity, metabolite and intermediate we list for Promethazine.

Promethazine impurities

Specifications & identifiers

Chemical identifiers
Product name	Promethazine N-Oxide
Catalogue No.	VQ-033350
CAS Number	81480-39-9
IUPAC name	N,N-dimethyl-1-phenothiazin-10-ylpropan-2-amine oxide
Molecular formula	C₁₇H₂₀N₂OS
Molecular weight	300.4 g/mol
Exact mass	300.1296
Grade	Reference Standard
HSN code	38229090
InChIKey	VSUIGOJNZBMHQV-UHFFFAOYSA-N
SMILES	CC(CN1C2=CC=CC=C2SC3=CC=CC=C31)[N+](C)(C)[O-]
PubChem CID	14424093

Physical properties
Physical form	Solid
LogP (XLogP3)	4.3
H-bond donors / acceptors	0 / 3
TPSA	46.6 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Promethazine N-Oxide?

The CAS Registry Number of Promethazine N-Oxide is 81480-39-9. It is also known as N,N-dimethyl-1-(10H-phenothiazin-10-yl)propan-2-amine oxide, Dimethyl[1-methyl-2-(10H-phenothiazin-10-yl)ethyl]amine oxide, 10H-Phenothiazine-10-ethanamine, N,N,alpha-trimethyl-, N-oxide.

What is the molecular formula and molecular weight of Promethazine N-Oxide?

Promethazine N-Oxide has the molecular formula C17H20N2OS and a molecular weight of 300.4 g/mol. Its IUPAC name is N,N-dimethyl-1-phenothiazin-10-ylpropan-2-amine oxide.

What is Promethazine N-Oxide used for?

Promethazine N-Oxide is supplied as a characterised reference material related to Promethazine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Promethazine N-Oxide can I order?

We supply Promethazine N-Oxide in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Promethazine N-Oxide?

Yes. Every lot of Promethazine N-Oxide is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Promethazine N-Oxide be shipped internationally?

Yes. We export Promethazine N-Oxide worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.