Promethazine-d6 Hydrochloride

Name: Promethazine-d6 Hydrochloride
Brand: Vaqora Chemicals
SKU: VQ-033355

About Promethazine-d6 Hydrochloride

Promethazine-d6 Hydrochloride (CAS 1189947-02-1) is a stable isotope labelled analogue related to Promethazine offered by Vaqora Chemicals. Formula C17H21ClN2S, molecular weight 326.9 g/mol. Common synonyms include Promethazine-d6 Hydrochloride Salt and TMID-0273.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

This isotope-labelled compound is used as an internal standard for LC-MS and LC-MS/MS quantitation of Promethazine and related analytes in bioanalytical, pharmacokinetic and impurity studies. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Promethazine-d6 Hydrochloride is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

LC-MS/MS internal standard
Bioanalytical quantitation
Pharmacokinetic studies

Industries

Related to Promethazine

View every impurity, metabolite and intermediate we list for Promethazine.

Promethazine impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Promethazine-d6 Hydrochloride
Catalogue No.	VQ-033355
CAS Number	1189947-02-1
IUPAC name	1-phenothiazin-10-yl-N,N-bis(trideuteriomethyl)propan-2-amine;hydrochloride
Molecular formula	C₁₇H₂₁ClN₂S
Molecular weight	326.9 g/mol
Exact mass	326.1491
Grade	Reference Standard
HSN code	38229090
InChIKey	XXPDBLUZJRXNNZ-HVTBMTIBSA-N
SMILES	[2H]C([2H])([2H])N(C(C)CN1C2=CC=CC=C2SC3=CC=CC=C31)C([2H])([2H])[2H].Cl
PubChem CID	46782787

Physical properties
Physical form	Solid
H-bond donors / acceptors	1 / 3
TPSA	31.8 Å²

Safety & hazard information (GHS)

Harmful / irritant

Environmental hazard

Signal word: Warning

Hazard statements

H302+H312+H332Harmful if swallowed, in contact with skin or if inhaled
H302Harmful if swallowed
H312Harmful in contact with skin
H315Causes skin irritation
H317May cause an allergic skin reaction
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation
H411Toxic to aquatic life with long lasting effects

Precautionary statements: P261, P264, P264 + P265, P270, P271, P272, P273, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P317, P319, P321, P330, P332 + P317, P333 + P317, P337 + P317, P362 + P364, P391, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Promethazine-d6 Hydrochloride?

The CAS Registry Number of Promethazine-d6 Hydrochloride is 1189947-02-1. It is also known as Promethazine-d6 Hydrochloride Salt, TMID-0273.

What is the molecular formula and molecular weight of Promethazine-d6 Hydrochloride?

Promethazine-d6 Hydrochloride has the molecular formula C17H21ClN2S and a molecular weight of 326.9 g/mol.

What is Promethazine-d6 Hydrochloride used for?

Promethazine-d6 Hydrochloride is supplied as a characterised reference material related to Promethazine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Promethazine-d6 Hydrochloride can I order?

We supply Promethazine-d6 Hydrochloride in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Promethazine-d6 Hydrochloride?

Yes. Every lot of Promethazine-d6 Hydrochloride is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Promethazine-d6 Hydrochloride be shipped internationally?

Yes. Promethazine-d6 Hydrochloride is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.