Promethazine Sulfoxide N-Oxide Hydrochloride 1135334-50-7

Name: Promethazine Sulfoxide N-Oxide Hydrochloride
Brand: Vaqora Chemicals
SKU: VQ-033352

About Promethazine Sulfoxide N-Oxide Hydrochloride

Vaqora Chemicals supplies Promethazine Sulfoxide N-Oxide Hydrochloride, a metabolite or degradation product of Promethazine registered under CAS number 1135334-50-7. The compound has the formula C17H21ClN2O2S, corresponding to a molecular weight of 352.9 g/mol. Common synonyms include Promethazine Sulfoxide N-Oxide HCl and Promethazine Sulphoxide N-Oxide Hydrochloride.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

It is used in metabolite identification, stability-indicating method development and impurity profiling of Promethazine, as well as in QC testing and ANDA/DMF documentation. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Promethazine

View every impurity, metabolite and intermediate we list for Promethazine.

Promethazine impurities

Specifications & identifiers

Chemical identifiers
Product name	Promethazine Sulfoxide N-Oxide Hydrochloride
Catalogue No.	VQ-033352
CAS Number	1135334-50-7
IUPAC name	N,N-dimethyl-1-(5-oxophenothiazin-10-yl)propan-2-amine oxide;hydrochloride
Molecular formula	C₁₇H₂₁ClN₂O₂S
Molecular weight	352.9 g/mol
Exact mass	352.1012
Grade	Reference Standard
HSN code	38229090
InChIKey	DLHPFOSVJVLDLK-UHFFFAOYSA-N
SMILES	CC(CN1C2=CC=CC=C2S(=O)C3=CC=CC=C31)[N+](C)(C)[O-].Cl
PubChem CID	25091454

Physical properties
Physical form	Solid
H-bond donors / acceptors	1 / 3
TPSA	68.3 Å²
Synonyms	10H-Phenothiazine-10-ethanamine, N,N,alpha-trimethyl-, N,5-dioxide, monohydrochloride, N,N,alpha-Trimethyl-10H-Phenothiazine-10-ethanamine N,5-Dioxide Hydrochloride (1:1), N,N,alpha-Trimethyl-10H-phenothiazine-10-ethanamine N,5-dioxide monohydrochloride, N,N-dimethyl-1-(5-oxido-10H-phenothiazin-10-yl)propan-2-amine oxide hydrochloride, Promethazine Sulfoxide N-Oxide HCl, Promethazine Sulphoxide N-Oxide Hydrochloride, 10H-Phenothiazine-10-ethanamine, N,N,alpha-trimethyl-, N,5-dioxide, hydrochloride (1:1)

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements: P264, P270, P301 + P317, P330, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Promethazine Sulfoxide N-Oxide Hydrochloride?

The CAS Registry Number of Promethazine Sulfoxide N-Oxide Hydrochloride is 1135334-50-7. It is also known as 10H-Phenothiazine-10-ethanamine, N,N,alpha-trimethyl-, N,5-dioxide, monohydrochloride, N,N,alpha-Trimethyl-10H-Phenothiazine-10-ethanamine N,5-Dioxide Hydrochloride (1:1), N,N,alpha-Trimethyl-10H-phenothiazine-10-ethanamine N,5-dioxide monohydrochloride.

What is the molecular formula and molecular weight of Promethazine Sulfoxide N-Oxide Hydrochloride?

Promethazine Sulfoxide N-Oxide Hydrochloride has the molecular formula C17H21ClN2O2S and a molecular weight of 352.9 g/mol.

What is Promethazine Sulfoxide N-Oxide Hydrochloride used for?

Promethazine Sulfoxide N-Oxide Hydrochloride is supplied as a characterised reference material related to Promethazine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Promethazine Sulfoxide N-Oxide Hydrochloride can I order?

We supply Promethazine Sulfoxide N-Oxide Hydrochloride in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Promethazine Sulfoxide N-Oxide Hydrochloride?

Yes. Every lot of Promethazine Sulfoxide N-Oxide Hydrochloride is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Promethazine Sulfoxide N-Oxide Hydrochloride be shipped internationally?

Yes. Promethazine Sulfoxide N-Oxide Hydrochloride is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.