Colchicine-d3

About Colchicine-d3

Colchicine-d3 is a stable isotope labelled analogue related to Colchicine carrying the CAS registry number 1217625-62-1. Formula C22H25NO6, molecular weight 402.5 g/mol. Systematically, it is named 2,2,2-trideuterio-N-[(7S)-1,2,3,10-tetramethoxy-9-oxo-6,7-dihydro-5H-benzo[a]heptalen-7-yl]acetamide. Alternative names: Colchicine-D3 (N-acetyl-D3) and TMID-1077.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Good laboratory practice and suitable PPE are recommended during handling.

This isotope-labelled compound is used as an internal standard for LC-MS and LC-MS/MS quantitation of Colchicine and related analytes in bioanalytical, pharmacokinetic and impurity studies. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

We offer Colchicine-d3 in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

LC-MS/MS internal standard
Bioanalytical quantitation
Pharmacokinetic studies

Industries

Related to Colchicine

View every impurity, metabolite and intermediate we list for Colchicine.

Colchicine impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Colchicine-d3
Catalogue No.	VQ-029925
CAS Number	1217625-62-1
IUPAC name	2,2,2-trideuterio-N-[(7S)-1,2,3,10-tetramethoxy-9-oxo-6,7-dihydro-5H-benzo[a]heptalen-7-yl]acetamide
Molecular formula	C₂₂H₂₅NO₆
Molecular weight	402.5 g/mol
Exact mass	402.187
Grade	Reference Standard
HSN code	38229090
InChIKey	IAKHMKGGTNLKSZ-AVSFSGARSA-N
SMILES	[2H]C([2H])([2H])C(=O)N[C@H]1CCC2=CC(=C(C(=C2C3=CC=C(C(=O)C=C13)OC)OC)OC)OC
PubChem CID	45038707

Physical properties
Physical form	Solid
LogP (XLogP3)	1
H-bond donors / acceptors	1 / 6
TPSA	83.1 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Colchicine-d3?

The CAS Registry Number of Colchicine-d3 is 1217625-62-1. It is also known as Colchicine-D3 (N-acetyl-D3), TMID-1077.

What is the molecular formula and molecular weight of Colchicine-d3?

Colchicine-d3 has the molecular formula C22H25NO6 and a molecular weight of 402.5 g/mol. Its IUPAC name is 2,2,2-trideuterio-N-[(7S)-1,2,3,10-tetramethoxy-9-oxo-6,7-dihydro-5H-benzo[a]heptalen-7-yl]acetamide.

What is Colchicine-d3 used for?

Colchicine-d3 is supplied as a characterised reference material related to Colchicine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Colchicine-d3 can I order?

We supply Colchicine-d3 in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Colchicine-d3?

Yes. Every lot of Colchicine-d3 is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Colchicine-d3 be shipped internationally?

Yes. We export Colchicine-d3 worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.