Ethinylestradiol EP Impurity B

Name: Ethinylestradiol EP Impurity B
Brand: Vaqora Chemicals
SKU: VQ-022574

About Ethinylestradiol EP Impurity B

Listed under CAS 1231-96-5, Ethinylestradiol EP Impurity B is a pharmacopeial impurity of Estradiol available from Vaqora Chemicals. Its molecular formula is C20H22O2 and its molecular weight is 294.4 g/mol. Its systematic (IUPAC) name is (8S,13S,14S,17R)-17-ethynyl-13-methyl-7,8,12,14,15,16-hexahydro-6H-cyclopenta[a]phenanthrene-3,17-diol. It is also known as 9,11-Dehydro Ethynyl Estradiol or Ethinylestradiol - Impurity B.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Under GHS it is labelled “Danger”, so handle it with suitable PPE and consult the SDS.

As a characterised impurity of Estradiol, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. It is used across pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Estradiol

View every impurity, metabolite and intermediate we list for Estradiol.

Estradiol impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Ethinylestradiol EP Impurity B
Catalogue No.	VQ-022574
CAS Number	1231-96-5
IUPAC name	(8S,13S,14S,17R)-17-ethynyl-13-methyl-7,8,12,14,15,16-hexahydro-6H-cyclopenta[a]phenanthrene-3,17-diol
Molecular formula	C₂₀H₂₂O₂
Molecular weight	294.4 g/mol
Exact mass	294.162
Grade	Reference Standard
HSN code	38229090
InChIKey	DUZHXWCAIBMQPI-FYQPLNBISA-N
SMILES	C[C@]12CC=C3[C@H]([C@@H]1CC[C@]2(C#C)O)CCC4=C3C=CC(=C4)O
PubChem CID	11150565

Physical properties
Physical form	Solid
LogP (XLogP3)	3.3
H-bond donors / acceptors	2 / 2
TPSA	40.5 Å²
Synonyms	9,11-Dehydro Ethynyl Estradiol, Ethinylestradiol - Impurity B, Ethynylestradiol EP Impurity B, 9,11-Dehydro ethynylestradiol, 19-Nor-17alpha-pregna-1,3,5(10),9(11)-tetraen-20-yne-3,17-diol, 19-Norpregna-1,3,5(10),9(11)-tetraen-20-yne-3,17-diol, (17alpha)-, Ethinylestradiol impurity B, Ethinylestradiol specified impurity B, delta9,11- Ethinyl estradiol, 9,11-DehydroEthynylEstradiol, delta-9(11)-Ethynylestradiol

Safety & hazard information (GHS)

Harmful / irritant

Health hazard

Environmental hazard

Signal word: Danger

Hazard statements

H302Harmful if swallowed
H350May cause cancer
H372Causes damage to organs through prolonged or repeated exposure
H400Very toxic to aquatic life
H410Very toxic to aquatic life with long lasting effects

Precautionary statements: P203, P260, P264, P270, P273, P280, P301 + P317, P318, P319, P330, P391, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Ethinylestradiol EP Impurity B?

The CAS Registry Number of Ethinylestradiol EP Impurity B is 1231-96-5. It is also known as 9,11-Dehydro Ethynyl Estradiol, Ethinylestradiol - Impurity B, Ethynylestradiol EP Impurity B.

What is the molecular formula and molecular weight of Ethinylestradiol EP Impurity B?

Ethinylestradiol EP Impurity B has the molecular formula C20H22O2 and a molecular weight of 294.4 g/mol. Its IUPAC name is (8S,13S,14S,17R)-17-ethynyl-13-methyl-7,8,12,14,15,16-hexahydro-6H-cyclopenta[a]phenanthrene-3,17-diol.

What is Ethinylestradiol EP Impurity B used for?

Ethinylestradiol EP Impurity B is supplied as a characterised reference material related to Estradiol. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Ethinylestradiol EP Impurity B can I order?

We supply Ethinylestradiol EP Impurity B in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Ethinylestradiol EP Impurity B?

Yes. Every lot of Ethinylestradiol EP Impurity B is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Ethinylestradiol EP Impurity B be shipped internationally?

Yes. Ethinylestradiol EP Impurity B is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.