Ivacaftor Carboxylic Acid

Name: Ivacaftor Carboxylic Acid
Brand: Vaqora Chemicals
SKU: VQ-031336

About Ivacaftor Carboxylic Acid

Ivacaftor Carboxylic Acid is an impurity of Ivacaftor carrying the CAS registry number 1246213-24-0. Formula C24H26N2O5, molecular weight 422.5 g/mol. The IUPAC name is 2-[5-tert-butyl-2-hydroxy-4-[(4-oxo-1H-quinoline-3-carbonyl)amino]phenyl]-2-methylpropanoic acid. It is also known as Ivacaftor Carboxylate or Ivacaftor (m6).

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Good laboratory practice and suitable PPE are recommended during handling.

This Ivacaftor impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. It is used across pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Ivacaftor Carboxylic Acid in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Ivacaftor

View every impurity, metabolite and intermediate we list for Ivacaftor.

Ivacaftor impurities

Specifications & identifiers

Chemical identifiers
Product name	Ivacaftor Carboxylic Acid
Catalogue No.	VQ-031336
CAS Number	1246213-24-0
IUPAC name	2-[5-tert-butyl-2-hydroxy-4-[(4-oxo-1H-quinoline-3-carbonyl)amino]phenyl]-2-methylpropanoic acid
Molecular formula	C₂₄H₂₆N₂O₅
Molecular weight	422.5 g/mol
Exact mass	422.1842
Grade	Reference Standard
HSN code	38229090
InChIKey	JYPYTFLCNPMVBC-UHFFFAOYSA-N
SMILES	CC(C)(C)C1=CC(=C(C=C1NC(=O)C2=CNC3=CC=CC=C3C2=O)O)C(C)(C)C(=O)O
PubChem CID	46917263

Physical properties
Physical form	Solid
LogP (XLogP3)	4.3
H-bond donors / acceptors	4 / 6
TPSA	116 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Ivacaftor Carboxylic Acid?

The CAS Registry Number of Ivacaftor Carboxylic Acid is 1246213-24-0. It is also known as Ivacaftor Carboxylate, Ivacaftor (m6).

What is the molecular formula and molecular weight of Ivacaftor Carboxylic Acid?

Ivacaftor Carboxylic Acid has the molecular formula C24H26N2O5 and a molecular weight of 422.5 g/mol. Its IUPAC name is 2-[5-tert-butyl-2-hydroxy-4-[(4-oxo-1H-quinoline-3-carbonyl)amino]phenyl]-2-methylpropanoic acid.

What is Ivacaftor Carboxylic Acid used for?

Ivacaftor Carboxylic Acid is supplied as a characterised reference material related to Ivacaftor. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Ivacaftor Carboxylic Acid can I order?

We supply Ivacaftor Carboxylic Acid in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Ivacaftor Carboxylic Acid?

Yes. Every lot of Ivacaftor Carboxylic Acid is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Ivacaftor Carboxylic Acid be shipped internationally?

Yes. We export Ivacaftor Carboxylic Acid worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.