Rilpivirine-d6

About Rilpivirine-d6

Rilpivirine-d6 is a stable isotope labelled analogue related to Rilpivirine carrying the CAS registry number 1312424-26-2. The compound has the formula C22H18N6, corresponding to a molecular weight of 372.5 g/mol. The IUPAC name is 4-[[4-[4-[(E)-2-cyanoethenyl]-2,6-bis(trideuteriomethyl)anilino]pyrimidin-2-yl]amino]benzonitrile.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Good laboratory practice and suitable PPE are recommended during handling.

Its mass shift relative to the unlabelled analyte makes it a dependable internal standard for LC-MS/MS assays, improving accuracy in bioanalysis, therapeutic drug monitoring and method validation. It is used across pharmaceutical manufacturing and academic and industrial research.

We offer Rilpivirine-d6 in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

LC-MS/MS internal standard
Bioanalytical quantitation
Pharmacokinetic studies

Industries

Related to Rilpivirine

View every impurity, metabolite and intermediate we list for Rilpivirine.

Rilpivirine impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Rilpivirine-d6
Catalogue No.	VQ-033545
CAS Number	1312424-26-2
IUPAC name	4-[[4-[4-[(E)-2-cyanoethenyl]-2,6-bis(trideuteriomethyl)anilino]pyrimidin-2-yl]amino]benzonitrile
Molecular formula	C₂₂H₁₈N₆
Molecular weight	372.5 g/mol
Exact mass	372.197
Grade	Reference Standard
HSN code	38229090
InChIKey	YIBOMRUWOWDFLG-XDMLVRQJSA-N
SMILES	[2H]C([2H])([2H])C1=CC(=CC(=C1NC2=NC(=NC=C2)NC3=CC=C(C=C3)C#N)C([2H])([2H])[2H])/C=C/C#N
PubChem CID	53240413

Physical properties
Physical form	Solid
LogP (XLogP3)	4.5
H-bond donors / acceptors	2 / 6
TPSA	97.4 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Rilpivirine-d6?

The CAS Registry Number of Rilpivirine-d6 is 1312424-26-2.

What is the molecular formula and molecular weight of Rilpivirine-d6?

Rilpivirine-d6 has the molecular formula C22H18N6 and a molecular weight of 372.5 g/mol. Its IUPAC name is 4-[[4-[4-[(E)-2-cyanoethenyl]-2,6-bis(trideuteriomethyl)anilino]pyrimidin-2-yl]amino]benzonitrile.

What is Rilpivirine-d6 used for?

Rilpivirine-d6 is supplied as a characterised reference material related to Rilpivirine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Rilpivirine-d6 can I order?

We supply Rilpivirine-d6 in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Rilpivirine-d6?

Yes. Every lot of Rilpivirine-d6 is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Rilpivirine-d6 be shipped internationally?

Yes. We export Rilpivirine-d6 worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.