Neratinib quinoline N-oxide

About Neratinib quinoline N-oxide

Neratinib quinoline N-oxide is a metabolite or degradation product of Neratinib carrying the CAS registry number 1348481-03-7. Its molecular formula is C30H29ClN6O4 and its molecular weight is 573.0 g/mol.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Handle it with standard laboratory precautions and appropriate personal protective equipment.

Analytical teams use this compound to identify metabolites and degradants of Neratinib, to validate stability-indicating methods (AMV) and to support QC and regulatory filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Neratinib quinoline N-oxide is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Neratinib

View every impurity, metabolite and intermediate we list for Neratinib.

Neratinib impurities

Specifications & identifiers

Chemical identifiers
Product name	Neratinib quinoline N-oxide
Catalogue No.	VQ-035485
CAS Number	1348481-03-7
IUPAC name	(E)-N-[4-[3-chloro-4-(pyridin-2-ylmethoxy)phenyl]imino-3-cyano-7-ethoxy-1-hydroxyquinolin-6-yl]-4-(dimethylamino)but-2-enamide
Molecular formula	C₃₀H₂₉ClN₆O₄
Molecular weight	573 g/mol
Exact mass	572.1939
Grade	Reference Standard
HSN code	38229090
InChIKey	MZADWDVYPKZCIE-SLLAKHMVSA-N
SMILES	CCOC1=C(C=C2C(=C1)N(C=C(C2=NC3=CC(=C(C=C3)OCC4=CC=CC=N4)Cl)C#N)O)NC(=O)/C=C/CN(C)C
PubChem CID	59198214

Physical properties
Physical form	Solid
LogP (XLogP3)	3.8
H-bond donors / acceptors	2 / 9
TPSA	123 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Neratinib quinoline N-oxide?

The CAS Registry Number of Neratinib quinoline N-oxide is 1348481-03-7.

What is the molecular formula and molecular weight of Neratinib quinoline N-oxide?

Neratinib quinoline N-oxide has the molecular formula C30H29ClN6O4 and a molecular weight of 573 g/mol. Its IUPAC name is (E)-N-[4-[3-chloro-4-(pyridin-2-ylmethoxy)phenyl]imino-3-cyano-7-ethoxy-1-hydroxyquinolin-6-yl]-4-(dimethylamino)but-2-enamide.

What is Neratinib quinoline N-oxide used for?

Neratinib quinoline N-oxide is supplied as a characterised reference material related to Neratinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Neratinib quinoline N-oxide can I order?

We supply Neratinib quinoline N-oxide in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Neratinib quinoline N-oxide?

Yes. Every lot of Neratinib quinoline N-oxide is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Neratinib quinoline N-oxide be shipped internationally?

Yes. We export Neratinib quinoline N-oxide worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.