Neratinib Dimethylamine N-Oxide(M7)

About Neratinib Dimethylamine N-Oxide(M7)

Neratinib Dimethylamine N-Oxide(M7) is a metabolite or degradation product of Neratinib carrying the CAS registry number 1376615-55-2. With the molecular formula C30H29ClN6O4, it has a molar mass of 573.0 g/mol. It is also known as Neratinib dimethylamine N-oxide or Neratinib metabolite M7.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Good laboratory practice and suitable PPE are recommended during handling.

It is used in metabolite identification, stability-indicating method development and impurity profiling of Neratinib, as well as in QC testing and ANDA/DMF documentation. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Neratinib

View every impurity, metabolite and intermediate we list for Neratinib.

Neratinib impurities

Specifications & identifiers

Chemical identifiers
Product name	Neratinib Dimethylamine N-Oxide(M7)
Catalogue No.	VQ-026872
CAS Number	1376615-55-2
IUPAC name	(E)-4-[[4-[3-chloro-4-(pyridin-2-ylmethoxy)anilino]-3-cyano-7-ethoxyquinolin-6-yl]amino]-N,N-dimethyl-4-oxobut-2-en-1-amine oxide
Molecular formula	C₃₀H₂₉ClN₆O₄
Molecular weight	573 g/mol
Exact mass	572.1939
Grade	Reference Standard
HSN code	38229090
InChIKey	DREVEVQWSRJACN-VQHVLOKHSA-N
SMILES	CCOC1=C(C=C2C(=C1)N=CC(=C2NC3=CC(=C(C=C3)OCC4=CC=CC=N4)Cl)C#N)NC(=O)/C=C/C[N+](C)(C)[O-]
PubChem CID	87687267

Physical properties
Physical form	Solid
LogP (XLogP3)	4.3
H-bond donors / acceptors	2 / 8
TPSA	127 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Neratinib Dimethylamine N-Oxide(M7)?

The CAS Registry Number of Neratinib Dimethylamine N-Oxide(M7) is 1376615-55-2. It is also known as Neratinib dimethylamine N-oxide, Neratinib metabolite M7, HKI-272 dimethylamine N-oxide.

What is the molecular formula and molecular weight of Neratinib Dimethylamine N-Oxide(M7)?

Neratinib Dimethylamine N-Oxide(M7) has the molecular formula C30H29ClN6O4 and a molecular weight of 573 g/mol. Its IUPAC name is (E)-4-[[4-[3-chloro-4-(pyridin-2-ylmethoxy)anilino]-3-cyano-7-ethoxyquinolin-6-yl]amino]-N,N-dimethyl-4-oxobut-2-en-1-amine oxide.

What is Neratinib Dimethylamine N-Oxide(M7) used for?

Neratinib Dimethylamine N-Oxide(M7) is supplied as a characterised reference material related to Neratinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Neratinib Dimethylamine N-Oxide(M7) can I order?

We supply Neratinib Dimethylamine N-Oxide(M7) in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Neratinib Dimethylamine N-Oxide(M7)?

Yes. Every lot of Neratinib Dimethylamine N-Oxide(M7) is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Neratinib Dimethylamine N-Oxide(M7) be shipped internationally?

Yes. We export Neratinib Dimethylamine N-Oxide(M7) worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.