Neratinib pyridine N-oxide (M3)

Name: Neratinib pyridine N-oxide (M3)
Brand: Vaqora Chemicals
SKU: VQ-023232

About Neratinib pyridine N-oxide (M3)

Listed under CAS 1376619-94-1, Neratinib pyridine N-oxide (M3) is a metabolite or degradation product of Neratinib available from Vaqora Chemicals. Formula C30H29ClN6O4, molecular weight 573.0 g/mol. Alternative names: Neratinib Pyridine N-Oxide and Neratinib metabolite M3.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

Analytical teams use this compound to identify metabolites and degradants of Neratinib, to validate stability-indicating methods (AMV) and to support QC and regulatory filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Neratinib pyridine N-oxide (M3) in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Neratinib

View every impurity, metabolite and intermediate we list for Neratinib.

Neratinib impurities

Specifications & identifiers

Chemical identifiers
Product name	Neratinib pyridine N-oxide (M3)
Catalogue No.	VQ-023232
CAS Number	1376619-94-1
IUPAC name	(E)-N-[4-[3-chloro-4-[(1-oxidopyridin-1-ium-2-yl)methoxy]anilino]-3-cyano-7-ethoxyquinolin-6-yl]-4-(dimethylamino)but-2-enamide
Molecular formula	C₃₀H₂₉ClN₆O₄
Molecular weight	573 g/mol
Exact mass	572.1939
Grade	Reference Standard
HSN code	38229090
InChIKey	CDFDEPYFRKSPTL-VQHVLOKHSA-N
SMILES	CCOC1=C(C=C2C(=C1)N=CC(=C2NC3=CC(=C(C=C3)OCC4=CC=CC=[N+]4[O-])Cl)C#N)NC(=O)/C=C/CN(C)C
PubChem CID	131634109

Physical properties
Physical form	Solid
LogP (XLogP3)	3.9
H-bond donors / acceptors	2 / 8
TPSA	125 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Neratinib pyridine N-oxide (M3)?

The CAS Registry Number of Neratinib pyridine N-oxide (M3) is 1376619-94-1. It is also known as Neratinib Pyridine N-Oxide, Neratinib metabolite M3, HKI-272 pyridine N-oxide.

What is the molecular formula and molecular weight of Neratinib pyridine N-oxide (M3)?

Neratinib pyridine N-oxide (M3) has the molecular formula C30H29ClN6O4 and a molecular weight of 573 g/mol. Its IUPAC name is (E)-N-[4-[3-chloro-4-[(1-oxidopyridin-1-ium-2-yl)methoxy]anilino]-3-cyano-7-ethoxyquinolin-6-yl]-4-(dimethylamino)but-2-enamide.

What is Neratinib pyridine N-oxide (M3) used for?

Neratinib pyridine N-oxide (M3) is supplied as a characterised reference material related to Neratinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Neratinib pyridine N-oxide (M3) can I order?

We supply Neratinib pyridine N-oxide (M3) in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Neratinib pyridine N-oxide (M3)?

Yes. Every lot of Neratinib pyridine N-oxide (M3) is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Neratinib pyridine N-oxide (M3) be shipped internationally?

Yes. We export Neratinib pyridine N-oxide (M3) worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.