Sitagliptin Impurity 40

About Sitagliptin Impurity 40

Sitagliptin Impurity 40 is a metabolite or degradation product of Sitagliptin carrying the CAS registry number 1459759-18-2. Formula C24H23F6N5O2, molecular weight 527.5 g/mol.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Good laboratory practice and suitable PPE are recommended during handling.

It is used in metabolite identification, stability-indicating method development and impurity profiling of Sitagliptin, as well as in QC testing and ANDA/DMF documentation. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide. A Safety Data Sheet (SDS) and technical specifications are available on request.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Sitagliptin

View every impurity, metabolite and intermediate we list for Sitagliptin.

Sitagliptin impurities

Specifications & identifiers

Chemical identifiers
Product name	Sitagliptin Impurity 40
Catalogue No.	VQ-033880
CAS Number	1459759-18-2
IUPAC name	(3R)-3-[[(1S)-2-hydroxy-1-phenylethyl]amino]-1-[3-(trifluoromethyl)-6,8-dihydro-5H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl]-4-(2,4,5-trifluorophenyl)butan-1-one
Molecular formula	C₂₄H₂₃F₆N₅O₂
Molecular weight	527.5 g/mol
Exact mass	527.1756
Grade	Reference Standard
HSN code	38229090
InChIKey	HWYDBEVIJSLSSI-OXQOHEQNSA-N
SMILES	C1CN2C(=NN=C2C(F)(F)F)CN1C(=O)C[C@@H](CC3=CC(=C(C=C3F)F)F)N[C@H](CO)C4=CC=CC=C4
PubChem CID	72948271

Physical properties
Physical form	Solid
LogP (XLogP3)	2.1
H-bond donors / acceptors	2 / 11
TPSA	83.3 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Sitagliptin Impurity 40?

The CAS Registry Number of Sitagliptin Impurity 40 is 1459759-18-2.

What is the molecular formula and molecular weight of Sitagliptin Impurity 40?

Sitagliptin Impurity 40 has the molecular formula C24H23F6N5O2 and a molecular weight of 527.5 g/mol. Its IUPAC name is (3R)-3-[[(1S)-2-hydroxy-1-phenylethyl]amino]-1-[3-(trifluoromethyl)-6,8-dihydro-5H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl]-4-(2,4,5-trifluorophenyl)butan-1-one.

What is Sitagliptin Impurity 40 used for?

Sitagliptin Impurity 40 is supplied as a characterised reference material related to Sitagliptin. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Sitagliptin Impurity 40 can I order?

We supply Sitagliptin Impurity 40 in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Sitagliptin Impurity 40?

Yes. Every lot of Sitagliptin Impurity 40 is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Sitagliptin Impurity 40 be shipped internationally?

Yes. We export Sitagliptin Impurity 40 worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.