(2S,4S)-Sacubitril Isomer

Name: (2S,4S)-Sacubitril Isomer
Brand: Vaqora Chemicals
SKU: VQ-004267

About (2S,4S)-Sacubitril Isomer

(2S,4S)-Sacubitril Isomer (CAS 149709-63-7) is an impurity of Sacubitril offered by Vaqora Chemicals. With the molecular formula C24H29NO5, it has a molar mass of 411.5 g/mol. The IUPAC name is 4-[[(2S,4S)-5-ethoxy-4-methyl-5-oxo-1-(4-phenylphenyl)pentan-2-yl]amino]-4-oxobutanoic acid. Alternative names: (2S,4S)-Sacubitril and Sacubitril, (2S,4S)-.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Good laboratory practice and suitable PPE are recommended during handling.

Pharmaceutical QC and development laboratories use this impurity standard of Sacubitril to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. It is used across pharmaceutical manufacturing and academic and industrial research.

We offer (2S,4S)-Sacubitril Isomer in 10 mg packs with a batch-specific COA, and ship to customers worldwide. Stock is available for quick dispatch.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Sacubitril

View every impurity, metabolite and intermediate we list for Sacubitril.

Sacubitril impurities

Specifications & identifiers

Chemical identifiers
Product name	(2S,4S)-Sacubitril Isomer
Catalogue No.	VQ-004267
CAS Number	149709-63-7
IUPAC name	4-[[(2S,4S)-5-ethoxy-4-methyl-5-oxo-1-(4-phenylphenyl)pentan-2-yl]amino]-4-oxobutanoic acid
Molecular formula	C₂₄H₂₉NO₅
Molecular weight	411.5 g/mol
Exact mass	411.2046
Grade	Reference Standard
HSN code	38229090
InChIKey	PYNXFZCZUAOOQC-UWJYYQICSA-N
SMILES	CCOC(=O)[C@@H](C)C[C@@H](CC1=CC=C(C=C1)C2=CC=CC=C2)NC(=O)CCC(=O)O
PubChem CID	122172973

Physical properties
Physical form	Solid
LogP (XLogP3)	3.7
H-bond donors / acceptors	2 / 5
TPSA	92.7 Å²
Synonyms	(2S,4S)-5-(Biphenyl-4-yl)-4-[(3-carboxypropionyl)amino]-2-methylpentanoic Acid Ethyl Ester, α-Ethyl (αS,γS)-γ-[(3-carboxy-1-oxopropyl)amino]-α-methyl[1,1′-biphenyl]-4-pentanoate, (2S,4S)-Sacubitril, Sacubitril, (2S,4S)-, Sacubitril (SS) diastereomer, 149709-63-7(free base), Sacubitril-(2S,4S)-Isomer calcium salt

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of (2S,4S)-Sacubitril Isomer?

The CAS Registry Number of (2S,4S)-Sacubitril Isomer is 149709-63-7. It is also known as (2S,4S)-5-(Biphenyl-4-yl)-4-[(3-carboxypropionyl)amino]-2-methylpentanoic Acid Ethyl Ester, α-Ethyl (αS,γS)-γ-[(3-carboxy-1-oxopropyl)amino]-α-methyl[1,1′-biphenyl]-4-pentanoate, (2S,4S)-Sacubitril.

What is the molecular formula and molecular weight of (2S,4S)-Sacubitril Isomer?

(2S,4S)-Sacubitril Isomer has the molecular formula C24H29NO5 and a molecular weight of 411.5 g/mol. Its IUPAC name is 4-[[(2S,4S)-5-ethoxy-4-methyl-5-oxo-1-(4-phenylphenyl)pentan-2-yl]amino]-4-oxobutanoic acid.

What is (2S,4S)-Sacubitril Isomer used for?

(2S,4S)-Sacubitril Isomer is supplied as a characterised reference material related to Sacubitril. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of (2S,4S)-Sacubitril Isomer can I order?

We supply (2S,4S)-Sacubitril Isomer in Reference Standard grade, in 10 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with (2S,4S)-Sacubitril Isomer?

Yes. Every lot of (2S,4S)-Sacubitril Isomer is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can (2S,4S)-Sacubitril Isomer be shipped internationally?

Yes. We export (2S,4S)-Sacubitril Isomer worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.