Bosentan Monohydrate

Name: Bosentan Monohydrate
Brand: Vaqora Chemicals
SKU: VQ-024619

About Bosentan Monohydrate

Listed under CAS 157212-55-0, Bosentan Monohydrate is a high-purity reference standard of Bosentan available from Vaqora Chemicals. Formula C27H31N5O7S, molecular weight 569.6 g/mol. It is also known as Bosentan Hydrate or Bosentan.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

Laboratories use this Bosentan standard for identity and assay testing, system suitability checks and method validation supporting ANDA and DMF filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Bosentan Monohydrate is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Bosentan

View every impurity, metabolite and intermediate we list for Bosentan.

Bosentan impurities

Specifications & identifiers

Chemical identifiers
Product name	Bosentan Monohydrate
Catalogue No.	VQ-024619
CAS Number	157212-55-0
IUPAC name	4-tert-butyl-N-[6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-2-pyrimidin-2-ylpyrimidin-4-yl]benzenesulfonamide;hydrate
Molecular formula	C₂₇H₃₁N₅O₇S
Molecular weight	569.6 g/mol
Exact mass	569.1944
Grade	Reference Standard
HSN code	38229090
InChIKey	SXTRWVVIEPWAKM-UHFFFAOYSA-N
SMILES	CC(C)(C)C1=CC=C(C=C1)S(=O)(=O)NC2=C(C(=NC(=N2)C3=NC=CC=N3)OCCO)OC4=CC=CC=C4OC.O
PubChem CID	185462

Physical properties
Physical form	Solid
H-bond donors / acceptors	3 / 12
TPSA	155 Å²
Synonyms	Bosentan Hydrate, Bosentan, Bosentan (hydrate), Bosentan (USAN), Bosentan hydrate (JAN), Tracleer, Bosentan monohydrate, CS-M0881

Safety & hazard information (GHS)

Harmful / irritant

Health hazard

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H312Harmful in contact with skin
H315Causes skin irritation
H317May cause an allergic skin reaction
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation
H361Suspected of damaging fertility or the unborn child
H412Harmful to aquatic life with long lasting effects

Precautionary statements: P203, P261, P264, P264 + P265, P270, P271, P272, P273, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P317, P318, P319, P321, P330, P332 + P317, P333 + P317, P337 + P317, P362 + P364, P403 + P233, P405

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Bosentan Monohydrate?

The CAS Registry Number of Bosentan Monohydrate is 157212-55-0. It is also known as Bosentan Hydrate, Bosentan, Bosentan (hydrate).

What is the molecular formula and molecular weight of Bosentan Monohydrate?

Bosentan Monohydrate has the molecular formula C27H31N5O7S and a molecular weight of 569.6 g/mol.

What is Bosentan Monohydrate used for?

Bosentan Monohydrate is supplied as a characterised reference material related to Bosentan. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Bosentan Monohydrate can I order?

We supply Bosentan Monohydrate in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Bosentan Monohydrate?

Yes. Every lot of Bosentan Monohydrate is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Bosentan Monohydrate be shipped internationally?

Yes. Bosentan Monohydrate is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.