Nintedanib D3

Name: Nintedanib D3
Brand: Vaqora Chemicals
SKU: VQ-038655

About Nintedanib D3

Nintedanib D3 is a stable isotope labelled analogue related to Nintedanib carrying the CAS registry number 1624587-84-3. Its molecular formula is C31H33N5O4 and its molecular weight is 542.6 g/mol. It is also known as Intedanib-d3 or TMIH-0393.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Good laboratory practice and suitable PPE are recommended during handling.

This isotope-labelled compound is used as an internal standard for LC-MS and LC-MS/MS quantitation of Nintedanib and related analytes in bioanalytical, pharmacokinetic and impurity studies. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Nintedanib D3 in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

LC-MS/MS internal standard
Bioanalytical quantitation
Pharmacokinetic studies

Industries

Related to Nintedanib

View every impurity, metabolite and intermediate we list for Nintedanib.

Nintedanib impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Nintedanib D3
Catalogue No.	VQ-038655
CAS Number	1624587-84-3
IUPAC name	methyl 2-hydroxy-3-[N-[4-[methyl-[2-[4-(trideuteriomethyl)piperazin-1-yl]acetyl]amino]phenyl]-C-phenylcarbonimidoyl]-1H-indole-6-carboxylate
Molecular formula	C₃₁H₃₃N₅O₄
Molecular weight	542.6 g/mol
Exact mass	542.2721
Grade	Reference Standard
HSN code	38229090
InChIKey	CPMDPSXJELVGJG-FIBGUPNXSA-N
SMILES	[2H]C([2H])([2H])N1CCN(CC1)CC(=O)N(C)C2=CC=C(C=C2)N=C(C3=CC=CC=C3)C4=C(NC5=C4C=CC(=C5)C(=O)OC)O
PubChem CID	136242406

Physical properties
Physical form	Solid
LogP (XLogP3)	4.3
H-bond donors / acceptors	2 / 7
TPSA	101 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Nintedanib D3?

The CAS Registry Number of Nintedanib D3 is 1624587-84-3. It is also known as Intedanib-d3, TMIH-0393.

What is the molecular formula and molecular weight of Nintedanib D3?

Nintedanib D3 has the molecular formula C31H33N5O4 and a molecular weight of 542.6 g/mol. Its IUPAC name is methyl 2-hydroxy-3-[N-[4-[methyl-[2-[4-(trideuteriomethyl)piperazin-1-yl]acetyl]amino]phenyl]-C-phenylcarbonimidoyl]-1H-indole-6-carboxylate.

What is Nintedanib D3 used for?

Nintedanib D3 is supplied as a characterised reference material related to Nintedanib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Nintedanib D3 can I order?

We supply Nintedanib D3 in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Nintedanib D3?

Yes. Every lot of Nintedanib D3 is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Nintedanib D3 be shipped internationally?

Yes. We export Nintedanib D3 worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.