5,6-Dihydro Tofacitinib

Name: 5,6-Dihydro Tofacitinib
Brand: Vaqora Chemicals
SKU: VQ-028416

About 5,6-Dihydro Tofacitinib

5,6-Dihydro Tofacitinib is an impurity of Tofacitinib carrying the CAS registry number 1640972-35-5. With the molecular formula C16H22N6O, it has a molar mass of 314.39 g/mol. It is also known as Tofacitinib-21.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Handle it with standard laboratory precautions and appropriate personal protective equipment.

As a characterised impurity of Tofacitinib, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies 5,6-Dihydro Tofacitinib in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Tofacitinib

View every impurity, metabolite and intermediate we list for Tofacitinib.

Tofacitinib impurities

Specifications & identifiers

Chemical identifiers
Product name	5,6-Dihydro Tofacitinib
Catalogue No.	VQ-028416
CAS Number	1640972-35-5
IUPAC name	3-[(3R,4R)-3-[6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidin-4-yl(methyl)amino]-4-methylpiperidin-1-yl]-3-oxopropanenitrile
Molecular formula	C₁₆H₂₂N₆O
Molecular weight	314.39 g/mol
Exact mass	314.1855
Grade	Reference Standard
HSN code	38229090
InChIKey	PEURVXMHTIUQCG-YPMHNXCESA-N
SMILES	C[C@@H]1CCN(C[C@@H]1N(C)C2=NC=NC3=C2CCN3)C(=O)CC#N
PubChem CID	67965295

Physical properties
Physical form	Solid
LogP (XLogP3)	1.4
H-bond donors / acceptors	1 / 6
TPSA	85.2 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 5,6-Dihydro Tofacitinib?

The CAS Registry Number of 5,6-Dihydro Tofacitinib is 1640972-35-5. It is also known as Tofacitinib-21, N-((3R,4R)-1-benzyl-4-methylpiperidin-3-yl)-N-methyl-7H-pyrrolo[2,3-d]pyrimidin-2-amine.

What is the molecular formula and molecular weight of 5,6-Dihydro Tofacitinib?

5,6-Dihydro Tofacitinib has the molecular formula C16H22N6O and a molecular weight of 314.39 g/mol. Its IUPAC name is 3-[(3R,4R)-3-[6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidin-4-yl(methyl)amino]-4-methylpiperidin-1-yl]-3-oxopropanenitrile.

What is 5,6-Dihydro Tofacitinib used for?

5,6-Dihydro Tofacitinib is supplied as a characterised reference material related to Tofacitinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 5,6-Dihydro Tofacitinib can I order?

We supply 5,6-Dihydro Tofacitinib in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 5,6-Dihydro Tofacitinib?

Yes. Every lot of 5,6-Dihydro Tofacitinib is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 5,6-Dihydro Tofacitinib be shipped internationally?

Yes. We export 5,6-Dihydro Tofacitinib worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.