2-Amino-4,6-di-tert-butylphenol

Name: 2-Amino-4,6-di-tert-butylphenol
Brand: Vaqora Chemicals
SKU: VQ-031337

About 2-Amino-4,6-di-tert-butylphenol

Vaqora Chemicals supplies 2-Amino-4,6-di-tert-butylphenol, an impurity of Ivacaftor registered under CAS number 1643-39-6. The compound has the formula C14H23NO, corresponding to a molecular weight of 221.34 g/mol. Alternative names: 6-Amino-2,4-di-tert-butylphenol and ADTBP cpd.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

Pharmaceutical QC and development laboratories use this impurity standard of Ivacaftor to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Ivacaftor

View every impurity, metabolite and intermediate we list for Ivacaftor.

Ivacaftor impurities

Specifications & identifiers

Chemical identifiers
Product name	2-Amino-4,6-di-tert-butylphenol
Catalogue No.	VQ-031337
CAS Number	1643-39-6
IUPAC name	2-amino-4,6-ditert-butylphenol
Molecular formula	C₁₄H₂₃NO
Molecular weight	221.34 g/mol
Exact mass	221.178
Grade	Reference Standard
HSN code	38229090
InChIKey	IVVMNEWWVJXCLX-UHFFFAOYSA-N
SMILES	CC(C)(C)C1=CC(=C(C(=C1)N)O)C(C)(C)C
PubChem CID	324555

Physical properties
Physical form	Solid
LogP (XLogP3)	4.2
H-bond donors / acceptors	2 / 2
TPSA	46.3 Å²
Synonyms	6-Amino-2,4-di-tert-butylphenol, ADTBP cpd, Phenol, 2-amino-4,6-bis(1,1-dimethylethyl)-, CBMicro_047984, Phenol, 2-amino-4,6-di-tert-butyl-, 2-amino-4,6-di-t-butylphenol, 2,4-di-tert-butyl-6-amino-phenol, 6-amino-2,4-di-tert-butyl-phenol

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H312Harmful in contact with skin
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P317, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 2-Amino-4,6-di-tert-butylphenol?

The CAS Registry Number of 2-Amino-4,6-di-tert-butylphenol is 1643-39-6. It is also known as 6-Amino-2,4-di-tert-butylphenol, ADTBP cpd, Phenol, 2-amino-4,6-bis(1,1-dimethylethyl)-.

What is the molecular formula and molecular weight of 2-Amino-4,6-di-tert-butylphenol?

2-Amino-4,6-di-tert-butylphenol has the molecular formula C14H23NO and a molecular weight of 221.34 g/mol. Its IUPAC name is 2-amino-4,6-ditert-butylphenol.

What is 2-Amino-4,6-di-tert-butylphenol used for?

2-Amino-4,6-di-tert-butylphenol is supplied as a characterised reference material related to Ivacaftor. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 2-Amino-4,6-di-tert-butylphenol can I order?

We supply 2-Amino-4,6-di-tert-butylphenol in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 2-Amino-4,6-di-tert-butylphenol?

Yes. Every lot of 2-Amino-4,6-di-tert-butylphenol is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 2-Amino-4,6-di-tert-butylphenol be shipped internationally?

Yes. 2-Amino-4,6-di-tert-butylphenol is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.