Naltrexone EP Impurity J

About Naltrexone EP Impurity J

Naltrexone EP Impurity J is a pharmacopeial impurity of Naltrexone carrying the CAS registry number 16617-07-5. Formula C21H25NO4, molecular weight 355.4 g/mol. It is also known as Naltrexone Hydrochloride - Impurity J or 3-Methoxynaltrexone.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Good laboratory practice and suitable PPE are recommended during handling.

As a characterised impurity of Naltrexone, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Naltrexone EP Impurity J is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Naltrexone

View every impurity, metabolite and intermediate we list for Naltrexone.

Naltrexone impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Naltrexone EP Impurity J
Catalogue No.	VQ-026824
CAS Number	16617-07-5
IUPAC name	(4R,4aS,7aR,12bS)-3-(cyclopropylmethyl)-4a-hydroxy-9-methoxy-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-7-one
Molecular formula	C₂₁H₂₅NO₄
Molecular weight	355.4 g/mol
Exact mass	355.1784
Grade	Reference Standard
HSN code	38229090
InChIKey	DSMNGWOUQMYTJH-MBPVOVBZSA-N
SMILES	COC1=C2C3=C(C[C@@H]4[C@]5([C@]3(CCN4CC6CC6)[C@@H](O2)C(=O)CC5)O)C=C1
PubChem CID	5487695

Physical properties
Physical form	Solid
LogP (XLogP3)	2.2
H-bond donors / acceptors	1 / 5
TPSA	59 Å²
Synonyms	Naltrexone Hydrochloride - Impurity J, 3-Methoxynaltrexone, 3-O-Methylnaltrexone, N-Cyclopropylmethylnoroxycodone, Naltrexone-3-methyl ether, Naltrexone 3-Methyl Ether, Naltrexone impurity J, Morphinan-6-one, 17-(cyclopropylmethyl)-4,5-epoxy-14-hydroxy-3-methoxy-, (5alpha)-, O3-Methyl-(-)-naltrexone, Methoxynaltrexone,3, N-Cyclopropylmethyl noroxycodone, Morphinan-6-one, 17-(cyclopropylmethyl)-4,5alpha-epoy-14-hydroxy-3-methoxy-

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Naltrexone EP Impurity J?

The CAS Registry Number of Naltrexone EP Impurity J is 16617-07-5. It is also known as Naltrexone Hydrochloride - Impurity J, 3-Methoxynaltrexone, 3-O-Methylnaltrexone.

What is the molecular formula and molecular weight of Naltrexone EP Impurity J?

Naltrexone EP Impurity J has the molecular formula C21H25NO4 and a molecular weight of 355.4 g/mol. Its IUPAC name is (4R,4aS,7aR,12bS)-3-(cyclopropylmethyl)-4a-hydroxy-9-methoxy-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-7-one.

What is Naltrexone EP Impurity J used for?

Naltrexone EP Impurity J is supplied as a characterised reference material related to Naltrexone. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Naltrexone EP Impurity J can I order?

We supply Naltrexone EP Impurity J in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Naltrexone EP Impurity J?

Yes. Every lot of Naltrexone EP Impurity J is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Naltrexone EP Impurity J be shipped internationally?

Yes. We export Naltrexone EP Impurity J worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.