Aprepitant Desfluoro Spot-1

Name: Aprepitant Desfluoro Spot-1
Brand: Vaqora Chemicals
SKU: VQ-004438

About Aprepitant Desfluoro Spot-1

Aprepitant Desfluoro Spot-1 is an impurity of Aprepitant carrying the CAS registry number 171338-33-3, specified at 99% purity. With the molecular formula C20H19F6NO2, it has a molar mass of 419.4 g/mol. Its systematic (IUPAC) name is (2R,3S)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-phenylmorpholine.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Good laboratory practice and suitable PPE are recommended during handling.

As a characterised impurity of Aprepitant, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. It is used across pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Aprepitant Desfluoro Spot-1 in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide. Stock is available for quick dispatch.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Aprepitant

View every impurity, metabolite and intermediate we list for Aprepitant.

Aprepitant impurities

Specifications & identifiers

Chemical identifiers
Product name	Aprepitant Desfluoro Spot-1
Catalogue No.	VQ-004438
CAS Number	171338-33-3
Other CAS	874460-46-5
IUPAC name	(2R,3S)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-phenylmorpholine
Molecular formula	C₂₀H₁₉F₆NO₂
Molecular weight	419.4 g/mol
Exact mass	419.132
Grade	Reference Standard
Purity / assay	99%
HSN code	38229090
InChIKey	UTDANMPTVJPQFZ-OCBCSQNSSA-N
SMILES	C[C@H](C1=CC(=CC(=C1)C(F)(F)F)C(F)(F)F)O[C@@H]2[C@@H](NCCO2)C3=CC=CC=C3
PubChem CID	10645742

Physical properties
Physical form	Solid
LogP (XLogP3)	4.6
H-bond donors / acceptors	1 / 9
TPSA	30.5 Å²
Synonyms	2-(R)-(1-(R)-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(S)-phenyl morpholine, (2R,3S)-2-((R)-1-(3,5-Bis(trifluoromethyl)phenyl)ethoxy)-3-phenylmorpholine, Morpholine, 2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-phenyl-,(2R,3S)-, (2R,3S)-2-{(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy}-3-phenylmorpholine, 2-(R)-(1-(R)-(3,5-bis(trifluoromethyl)-phenyl)ethoxy)-3-(S)-phenyl morpholine, 2-[(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-phenylmorpholine, (2R,3S)-

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Aprepitant Desfluoro Spot-1?

The CAS Registry Number of Aprepitant Desfluoro Spot-1 is 171338-33-3. It is also known as 2-(R)-(1-(R)-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(S)-phenyl morpholine, (2R,3S)-2-((R)-1-(3,5-Bis(trifluoromethyl)phenyl)ethoxy)-3-phenylmorpholine, Morpholine, 2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-phenyl-,(2R,3S)-.

What is the molecular formula and molecular weight of Aprepitant Desfluoro Spot-1?

Aprepitant Desfluoro Spot-1 has the molecular formula C20H19F6NO2 and a molecular weight of 419.4 g/mol. Its IUPAC name is (2R,3S)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-phenylmorpholine.

What is Aprepitant Desfluoro Spot-1 used for?

Aprepitant Desfluoro Spot-1 is supplied as a characterised reference material related to Aprepitant. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Aprepitant Desfluoro Spot-1 can I order?

We supply Aprepitant Desfluoro Spot-1 in Reference Standard (99%) grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Aprepitant Desfluoro Spot-1?

Yes. Every lot of Aprepitant Desfluoro Spot-1 is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Aprepitant Desfluoro Spot-1 be shipped internationally?

Yes. We export Aprepitant Desfluoro Spot-1 worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.