N-Methylcarbonyl-2-chloroacetamidrazone

Name: N-Methylcarbonyl-2-chloroacetamidrazone
Brand: Vaqora Chemicals
SKU: VQ-023373

About N-Methylcarbonyl-2-chloroacetamidrazone

N-Methylcarbonyl-2-chloroacetamidrazone is an impurity of Aprepitant carrying the CAS registry number 155742-64-6. The compound has the formula C4H8ClN3O2, corresponding to a molecular weight of 165.58 g/mol. Its systematic (IUPAC) name is methyl N-[(Z)-(1-amino-2-chloroethylidene)amino]carbamate. Alternative names: N-methoxy carbonyl-2-chloroacetamidrazone.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

Pharmaceutical QC and development laboratories use this impurity standard of Aprepitant to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. It is used across pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Aprepitant

View every impurity, metabolite and intermediate we list for Aprepitant.

Aprepitant impurities

Specifications & identifiers

Chemical identifiers
Product name	N-Methylcarbonyl-2-chloroacetamidrazone
Catalogue No.	VQ-023373
CAS Number	155742-64-6
IUPAC name	methyl N-[(Z)-(1-amino-2-chloroethylidene)amino]carbamate
Molecular formula	C₄H₈ClN₃O₂
Molecular weight	165.58 g/mol
Exact mass	165.0305
Grade	Reference Standard
HSN code	38229090
InChIKey	JAIGTTPBXVVFPN-UHFFFAOYSA-N
SMILES	COC(=O)N/N=C(/CCl)\N
PubChem CID	11435142

Physical properties
Physical form	Solid
H-bond donors / acceptors	2 / 3
TPSA	76.7 Å²
Synonyms	N-methoxy carbonyl-2-chloroacetamidrazone, Methyl 2-(2-chloro-1-iminoethyl)hydrazinecarboxylate, 2-(2-Chloro-1-iminoethyl)hydrazinecarboxylic Acid Methyl Ester, (Z)-Methyl 2-(1-amino-2-chloroethylidene)hydrazinecarboxylate, Methyl 2-(1-amino-2-chloroethylidene)hydrazinecarboxylate, Hydrazinecarboxylicacid, 2-(2-chloro-1-iminoethyl)-, methyl ester, Hydrazinecarboxylic acid, 2-(2-chloro-1-iminoethyl)-, methyl ester, Methyl 2-(2-chloro-1-iminoethyl)-hydrazinecarboxylate, (Z)-Methyl2-(1-amino-2-chloroethylidene)hydrazinecarboxylate, N'-(2-chloroethanimidoyl)methoxycarbohydrazide, Methyl (2Z)-2-(1-amino-2-chloroethylidene)hydrazine-1-carboxylate

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of N-Methylcarbonyl-2-chloroacetamidrazone?

The CAS Registry Number of N-Methylcarbonyl-2-chloroacetamidrazone is 155742-64-6. It is also known as N-methoxy carbonyl-2-chloroacetamidrazone, Methyl 2-(2-chloro-1-iminoethyl)hydrazinecarboxylate, 2-(2-Chloro-1-iminoethyl)hydrazinecarboxylic Acid Methyl Ester.

What is the molecular formula and molecular weight of N-Methylcarbonyl-2-chloroacetamidrazone?

N-Methylcarbonyl-2-chloroacetamidrazone has the molecular formula C4H8ClN3O2 and a molecular weight of 165.58 g/mol. Its IUPAC name is methyl N-[(Z)-(1-amino-2-chloroethylidene)amino]carbamate.

What is N-Methylcarbonyl-2-chloroacetamidrazone used for?

N-Methylcarbonyl-2-chloroacetamidrazone is supplied as a characterised reference material related to Aprepitant. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of N-Methylcarbonyl-2-chloroacetamidrazone can I order?

We supply N-Methylcarbonyl-2-chloroacetamidrazone in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with N-Methylcarbonyl-2-chloroacetamidrazone?

Yes. Every lot of N-Methylcarbonyl-2-chloroacetamidrazone is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can N-Methylcarbonyl-2-chloroacetamidrazone be shipped internationally?

Yes. We export N-Methylcarbonyl-2-chloroacetamidrazone worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.