(R,R,R)-Aprepitant

Name: (R,R,R)-Aprepitant
Brand: Vaqora Chemicals
SKU: VQ-024339

About (R,R,R)-Aprepitant

(R,R,R)-Aprepitant (CAS 1148113-53-4) is a high-purity reference standard of Aprepitant offered by Vaqora Chemicals. Formula C23H21F7N4O3, molecular weight 534.4 g/mol. Common synonyms include (1R,2R,3R)-Aprepitant and Aprepitant, (R,R,R)-.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

As a reference sample of Aprepitant, it is used for identification, assay and impurity-profiling work during analytical method development, validation (AMV) and routine QC. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Aprepitant

View every impurity, metabolite and intermediate we list for Aprepitant.

Aprepitant impurities

Specifications & identifiers

Chemical identifiers
Product name	(R,R,R)-Aprepitant
Catalogue No.	VQ-024339
CAS Number	1148113-53-4
IUPAC name	3-[[(2R,3R)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholin-4-yl]methyl]-1,4-dihydro-1,2,4-triazol-5-one
Molecular formula	C₂₃H₂₁F₇N₄O₃
Molecular weight	534.4 g/mol
Exact mass	534.1502
Grade	Reference Standard
HSN code	38229090
InChIKey	ATALOFNDEOCMKK-TVNIXMEMSA-N
SMILES	C[C@H](C1=CC(=CC(=C1)C(F)(F)F)C(F)(F)F)O[C@@H]2[C@H](N(CCO2)CC3=NNC(=O)N3)C4=CC=C(C=C4)F
PubChem CID	135925275

Physical properties
Physical form	Solid
LogP (XLogP3)	4.2
H-bond donors / acceptors	2 / 12
TPSA	75.2 Å²

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H413May cause long lasting harmful effects to aquatic life

Precautionary statements: P264, P270, P273, P301 + P317, P330, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of (R,R,R)-Aprepitant?

The CAS Registry Number of (R,R,R)-Aprepitant is 1148113-53-4. It is also known as (1R,2R,3R)-Aprepitant, Aprepitant, (R,R,R)-.

What is the molecular formula and molecular weight of (R,R,R)-Aprepitant?

(R,R,R)-Aprepitant has the molecular formula C23H21F7N4O3 and a molecular weight of 534.4 g/mol. Its IUPAC name is 3-[[(2R,3R)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholin-4-yl]methyl]-1,4-dihydro-1,2,4-triazol-5-one.

What is (R,R,R)-Aprepitant used for?

(R,R,R)-Aprepitant is supplied as a characterised reference material related to Aprepitant. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of (R,R,R)-Aprepitant can I order?

We supply (R,R,R)-Aprepitant in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with (R,R,R)-Aprepitant?

Yes. Every lot of (R,R,R)-Aprepitant is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can (R,R,R)-Aprepitant be shipped internationally?

Yes. (R,R,R)-Aprepitant is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.