O-Des Methyl Osimertinib Intermediate (Stage-… 1801616-73-8

Name: O-Des Methyl Osimertinib Intermediate (Stage-1)
Brand: Vaqora Chemicals
SKU: VQ-013671

About O-Des Methyl Osimertinib Intermediate (Stage-1)

O-Des Methyl Osimertinib Intermediate (Stage-1) (CAS 1801616-73-8) is a process intermediate or related compound of Osimertinib offered by Vaqora Chemicals, specified at 97.06% purity. With the molecular formula C20H18FN5O, it has a molar mass of 363.4 g/mol. Systematically, it is named 4-fluoro-6-methoxy-1-N-[4-(1-methylindol-3-yl)pyrimidin-2-yl]benzene-1,3-diamine.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Good laboratory practice and suitable PPE are recommended during handling.

Process chemists and analysts use it when developing synthetic routes to Osimertinib, tracking process-related impurities and validating analytical methods. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

We offer O-Des Methyl Osimertinib Intermediate (Stage-1) in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide. Stock is available for quick dispatch.

Typical applications

API route development
Impurity fate & purge studies
Analytical method development

Industries

Related to Osimertinib

View every impurity, metabolite and intermediate we list for Osimertinib.

Osimertinib impurities

Specifications & identifiers

Chemical identifiers
Product name	O-Des Methyl Osimertinib Intermediate (Stage-1)
Catalogue No.	VQ-013671
CAS Number	1801616-73-8
IUPAC name	4-fluoro-6-methoxy-1-N-[4-(1-methylindol-3-yl)pyrimidin-2-yl]benzene-1,3-diamine
Molecular formula	C₂₀H₁₈FN₅O
Molecular weight	363.4 g/mol
Exact mass	363.1495
Grade	Reference Standard
Purity / assay	97.06%
HSN code	2933
InChIKey	XGCRDQKFYXFXHA-UHFFFAOYSA-N
SMILES	CN1C=C(C2=CC=CC=C21)C3=NC(=NC=C3)NC4=C(C=C(C(=C4)N)F)OC
PubChem CID	141509363

Physical properties
Physical form	Solid
LogP (XLogP3)	3.2
H-bond donors / acceptors	2 / 6
TPSA	78 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of O-Des Methyl Osimertinib Intermediate (Stage-1)?

The CAS Registry Number of O-Des Methyl Osimertinib Intermediate (Stage-1) is 1801616-73-8. It is also known as 4-fluoro-6-methoxy-N1-(4-(1-methyl-1H-indol-3-yl)pyrimidin-2-yl)benzene-1,3-diamine, 1,3-Benzenediamine, 4-fluoro-6-methoxy-N1-[4-(1-methyl-1H-indol-3-yl)-2-pyrimidinyl]-.

What is the molecular formula and molecular weight of O-Des Methyl Osimertinib Intermediate (Stage-1)?

O-Des Methyl Osimertinib Intermediate (Stage-1) has the molecular formula C20H18FN5O and a molecular weight of 363.4 g/mol. Its IUPAC name is 4-fluoro-6-methoxy-1-N-[4-(1-methylindol-3-yl)pyrimidin-2-yl]benzene-1,3-diamine.

What is O-Des Methyl Osimertinib Intermediate (Stage-1) used for?

O-Des Methyl Osimertinib Intermediate (Stage-1) is supplied as a characterised reference material related to Osimertinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of O-Des Methyl Osimertinib Intermediate (Stage-1) can I order?

We supply O-Des Methyl Osimertinib Intermediate (Stage-1) in Reference Standard (97.06%) grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with O-Des Methyl Osimertinib Intermediate (Stage-1)?

Yes. Every lot of O-Des Methyl Osimertinib Intermediate (Stage-1) is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can O-Des Methyl Osimertinib Intermediate (Stage-1) be shipped internationally?

Yes. We export O-Des Methyl Osimertinib Intermediate (Stage-1) worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.