Levothyroxine EP Impurity H (Stage -6)

About Levothyroxine EP Impurity H (Stage -6)

Levothyroxine EP Impurity H (Stage -6) is a pharmacopeial impurity of Levothyroxine carrying the CAS registry number 1838-55-7. Formula C13H8I2O4, molecular weight 482.01 g/mol. The IUPAC name is 4-(4-hydroxyphenoxy)-3,5-diiodobenzoic acid. It is also known as 3,5-Diiodo-4-(4'-hydroxyphenoxy)benzoic acid or 3,5-Diiodothyroformic Acid.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Good laboratory practice and suitable PPE are recommended during handling.

Pharmaceutical QC and development laboratories use this impurity standard of Levothyroxine to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide. Stock is available for quick dispatch.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Levothyroxine

View every impurity, metabolite and intermediate we list for Levothyroxine.

Levothyroxine impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Levothyroxine EP Impurity H (Stage -6)
Catalogue No.	VQ-006482
CAS Number	1838-55-7
IUPAC name	4-(4-hydroxyphenoxy)-3,5-diiodobenzoic acid
Molecular formula	C₁₃H₈I₂O₄
Molecular weight	482.01 g/mol
Exact mass	481.8512
Grade	Reference Standard
HSN code	38229090
InChIKey	LPNQFIJWELQLRO-UHFFFAOYSA-N
SMILES	C1=CC(=CC=C1O)OC2=C(C=C(C=C2I)C(=O)O)I
PubChem CID	12961897

Physical properties
Physical form	Solid
LogP (XLogP3)	3.9
H-bond donors / acceptors	2 / 4
TPSA	66.8 Å²
Synonyms	3,5-Diiodo-4-(4'-hydroxyphenoxy)benzoic acid, 3,5-Diiodothyroformic Acid, 4-(p-Hydroxyphenoxy)-3,5-diiodobenzoic Acid, Levothyroxine EP Impurity H ( Stage -6), starbld0005200, 4-(4-hydroxy-phenoxy)-3,5-diiodobenzoic acid

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Levothyroxine EP Impurity H (Stage -6)?

The CAS Registry Number of Levothyroxine EP Impurity H (Stage -6) is 1838-55-7. It is also known as 3,5-Diiodo-4-(4'-hydroxyphenoxy)benzoic acid, 3,5-Diiodothyroformic Acid, 4-(p-Hydroxyphenoxy)-3,5-diiodobenzoic Acid.

What is the molecular formula and molecular weight of Levothyroxine EP Impurity H (Stage -6)?

Levothyroxine EP Impurity H (Stage -6) has the molecular formula C13H8I2O4 and a molecular weight of 482.01 g/mol. Its IUPAC name is 4-(4-hydroxyphenoxy)-3,5-diiodobenzoic acid.

What is Levothyroxine EP Impurity H (Stage -6) used for?

Levothyroxine EP Impurity H (Stage -6) is supplied as a characterised reference material related to Levothyroxine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Levothyroxine EP Impurity H (Stage -6) can I order?

We supply Levothyroxine EP Impurity H (Stage -6) in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Levothyroxine EP Impurity H (Stage -6)?

Yes. Every lot of Levothyroxine EP Impurity H (Stage -6) is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Levothyroxine EP Impurity H (Stage -6) be shipped internationally?

Yes. We export Levothyroxine EP Impurity H (Stage -6) worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.