Afatinib 3,4-dichlorophenyl Amine Impurity 2044709-79-5

Name: Afatinib 3,4-dichlorophenyl Amine Impurity
Brand: Vaqora Chemicals
SKU: VQ-035328

About Afatinib 3,4-dichlorophenyl Amine Impurity

Vaqora Chemicals supplies Afatinib 3,4-dichlorophenyl Amine Impurity, an impurity of Afatinib registered under CAS number 2044709-79-5. With the molecular formula C18H16Cl2N4O2, it has a molar mass of 391.2 g/mol. Its systematic (IUPAC) name is 4-N-(3,4-dichlorophenyl)-7-[(3S)-oxolan-3-yl]oxyquinazoline-4,6-diamine.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Good laboratory practice and suitable PPE are recommended during handling.

Pharmaceutical QC and development laboratories use this impurity standard of Afatinib to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Afatinib 3,4-dichlorophenyl Amine Impurity is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Afatinib

View every impurity, metabolite and intermediate we list for Afatinib.

Afatinib impurities

Specifications & identifiers

Chemical identifiers
Product name	Afatinib 3,4-dichlorophenyl Amine Impurity
Catalogue No.	VQ-035328
CAS Number	2044709-79-5
IUPAC name	4-N-(3,4-dichlorophenyl)-7-[(3S)-oxolan-3-yl]oxyquinazoline-4,6-diamine
Molecular formula	C₁₈H₁₆Cl₂N₄O₂
Molecular weight	391.2 g/mol
Exact mass	390.065
Grade	Reference Standard
HSN code	38229090
InChIKey	BWMFVFPCIQVGNU-NSHDSACASA-N
SMILES	C1COC[C@H]1OC2=C(C=C3C(=C2)N=CN=C3NC4=CC(=C(C=C4)Cl)Cl)N
PubChem CID	127255548

Physical properties
Physical form	Solid
LogP (XLogP3)	4
H-bond donors / acceptors	2 / 6
TPSA	82.3 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Afatinib 3,4-dichlorophenyl Amine Impurity?

The CAS Registry Number of Afatinib 3,4-dichlorophenyl Amine Impurity is 2044709-79-5. It is also known as (S)-N4-(3,4-Dichlorophenyl)-7-((tetrahydrofuran-3-yl)oxy)quinazoline-4,6-diamine, N4-(3,4-dichlorophenyl)-7-[(3S)-oxolan-3-yloxy]quinazoline-4,6-diamine.

What is the molecular formula and molecular weight of Afatinib 3,4-dichlorophenyl Amine Impurity?

Afatinib 3,4-dichlorophenyl Amine Impurity has the molecular formula C18H16Cl2N4O2 and a molecular weight of 391.2 g/mol. Its IUPAC name is 4-N-(3,4-dichlorophenyl)-7-[(3S)-oxolan-3-yl]oxyquinazoline-4,6-diamine.

What is Afatinib 3,4-dichlorophenyl Amine Impurity used for?

Afatinib 3,4-dichlorophenyl Amine Impurity is supplied as a characterised reference material related to Afatinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Afatinib 3,4-dichlorophenyl Amine Impurity can I order?

We supply Afatinib 3,4-dichlorophenyl Amine Impurity in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Afatinib 3,4-dichlorophenyl Amine Impurity?

Yes. Every lot of Afatinib 3,4-dichlorophenyl Amine Impurity is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Afatinib 3,4-dichlorophenyl Amine Impurity be shipped internationally?

Yes. We export Afatinib 3,4-dichlorophenyl Amine Impurity worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.