Ticagrelor EP Impurity E

About Ticagrelor EP Impurity E

Ticagrelor EP Impurity E is a pharmacopeial impurity of Ticagrelor carrying the CAS registry number 220352-38-5. With the molecular formula C9H9F2N, it has a molar mass of 169.17 g/mol. The IUPAC name is trans-(1R,2S)-2-(3,4-difluorophenyl)cyclopropan-1-amine. Common synonyms include Ticagrelor Related Compound A and Ticagrelor Impurity E.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

This Ticagrelor impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

We offer Ticagrelor EP Impurity E in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Ticagrelor

View every impurity, metabolite and intermediate we list for Ticagrelor.

Ticagrelor impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Ticagrelor EP Impurity E
Catalogue No.	VQ-028372
CAS Number	220352-38-5
IUPAC name	trans-(1R,2S)-2-(3,4-difluorophenyl)cyclopropan-1-amine
Molecular formula	C₉H₉F₂N
Molecular weight	169.17 g/mol
Exact mass	169.0703
Grade	Reference Standard
HSN code	38229090
InChIKey	QVUBIQNXHRPJKK-IMTBSYHQSA-N
SMILES	C1[C@H]([C@@H]1N)C2=CC(=C(C=C2)F)F
PubChem CID	9834068

Physical properties
Physical form	Solid
LogP (XLogP3)	1.4
H-bond donors / acceptors	1 / 3
TPSA	26 Å²
Synonyms	Ticagrelor Related Compound A, (1R,2S)-2-(3,4-Difluorophenyl)cyclopropanamine, (1R,2S)-2-(3,4-difluorophenyl)cyclopropylamine, 2-(3,4-Difluorophenyl)cyclopropanamine, (1R,2S)-, (1R,2S)-rel-2-(3,4-Difluorophenyl)cyclopropanamine, Cyclopropanamine, 2-(3,4-difluorophenyl)-, (1R,2S)-, rac-(1R,2S)-2-(3,4-difluorophenyl)cyclopropan-1-amine, Cyclopropanamine, 2-(3,4-difluorophenyl)-, (1R,2S)-rel-, (1R, 2S)-Rel-2-(3, 4-Difluorophenyl)cyclopropanamine, Ticagrelor Impurity E, Ticagrelor Related Compound cent section sign, (1r-trans)-2-(3,4-difluorophenyl)cyclopropanamine

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P271, P280, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Ticagrelor EP Impurity E?

The CAS Registry Number of Ticagrelor EP Impurity E is 220352-38-5. It is also known as Ticagrelor Related Compound A, (1R,2S)-2-(3,4-Difluorophenyl)cyclopropanamine, (1R,2S)-2-(3,4-difluorophenyl)cyclopropylamine.

What is the molecular formula and molecular weight of Ticagrelor EP Impurity E?

Ticagrelor EP Impurity E has the molecular formula C9H9F2N and a molecular weight of 169.17 g/mol. Its IUPAC name is trans-(1R,2S)-2-(3,4-difluorophenyl)cyclopropan-1-amine.

What is Ticagrelor EP Impurity E used for?

Ticagrelor EP Impurity E is supplied as a characterised reference material related to Ticagrelor. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Ticagrelor EP Impurity E can I order?

We supply Ticagrelor EP Impurity E in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Ticagrelor EP Impurity E?

Yes. Every lot of Ticagrelor EP Impurity E is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Ticagrelor EP Impurity E be shipped internationally?

Yes. Ticagrelor EP Impurity E is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.