Amlodipine EP Impurity C [Stage (N-1)]

About Amlodipine EP Impurity C [Stage (N-1)]

Amlodipine EP Impurity C [Stage (N-1)] is a pharmacopeial impurity of Amlodipine carrying the CAS registry number 223734-99-4. Formula C38H34ClN3O10, molecular weight 728.1 g/mol. It is also known as Bis Phthaloyl Amlodipine or Amlodipine Intermediate 6.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Good laboratory practice and suitable PPE are recommended during handling.

Pharmaceutical QC and development laboratories use this impurity standard of Amlodipine to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. It is used across pharmaceutical manufacturing and academic and industrial research.

We offer Amlodipine EP Impurity C [Stage (N-1)] in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Amlodipine

View every impurity, metabolite and intermediate we list for Amlodipine.

Amlodipine impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Amlodipine EP Impurity C [Stage (N-1)]
Catalogue No.	VQ-006229
CAS Number	223734-99-4
IUPAC name	5-O-ethyl 3-O-methyl 4-(2-chlorophenyl)-2,6-bis[2-(1,3-dioxoisoindol-2-yl)ethoxymethyl]-1,4-dihydropyridine-3,5-dicarboxylate
Molecular formula	C₃₈H₃₄ClN₃O₁₀
Molecular weight	728.1 g/mol
Exact mass	727.1933
Grade	Reference Standard
HSN code	38229090
InChIKey	BYCSTJYIYIUNQA-UHFFFAOYSA-N
SMILES	CCOC(=O)C1=C(NC(=C(C1C2=CC=CC=C2Cl)C(=O)OC)COCCN3C(=O)C4=CC=CC=C4C3=O)COCCN5C(=O)C6=CC=CC=C6C5=O
PubChem CID	131667667

Physical properties
Physical form	Solid
LogP (XLogP3)	4.6
H-bond donors / acceptors	1 / 11
TPSA	158 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Amlodipine EP Impurity C [Stage (N-1)]?

The CAS Registry Number of Amlodipine EP Impurity C [Stage (N-1)] is 223734-99-4. It is also known as Bis Phthaloyl Amlodipine, Amlodipine Intermediate 6.

What is the molecular formula and molecular weight of Amlodipine EP Impurity C [Stage (N-1)]?

Amlodipine EP Impurity C [Stage (N-1)] has the molecular formula C38H34ClN3O10 and a molecular weight of 728.1 g/mol. Its IUPAC name is 5-O-ethyl 3-O-methyl 4-(2-chlorophenyl)-2,6-bis[2-(1,3-dioxoisoindol-2-yl)ethoxymethyl]-1,4-dihydropyridine-3,5-dicarboxylate.

What is Amlodipine EP Impurity C [Stage (N-1)] used for?

Amlodipine EP Impurity C [Stage (N-1)] is supplied as a characterised reference material related to Amlodipine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Amlodipine EP Impurity C [Stage (N-1)] can I order?

We supply Amlodipine EP Impurity C [Stage (N-1)] in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Amlodipine EP Impurity C [Stage (N-1)]?

Yes. Every lot of Amlodipine EP Impurity C [Stage (N-1)] is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Amlodipine EP Impurity C [Stage (N-1)] be shipped internationally?

Yes. We export Amlodipine EP Impurity C [Stage (N-1)] worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.