Nintedanib Impurity F (Intermediate)

About Nintedanib Impurity F (Intermediate)

Nintedanib Impurity F (Intermediate) is an impurity of Nintedanib carrying the CAS registry number 2410649-54-4. Its molecular formula is C22H26N6O6 and its molecular weight is 470.5 g/mol. Its systematic (IUPAC) name is N-methyl-2-[4-[2-(N-methyl-4-nitroanilino)-2-oxoethyl]piperazin-1-yl]-N-(4-nitrophenyl)acetamide. Common synonyms include Nintedanib Impurity 52.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Handle it with standard laboratory precautions and appropriate personal protective equipment.

As a characterised impurity of Nintedanib, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

We offer Nintedanib Impurity F (Intermediate) in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide. Stock is available for quick dispatch.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Nintedanib

View every impurity, metabolite and intermediate we list for Nintedanib.

Nintedanib impurities

Specifications & identifiers

Chemical identifiers
Product name	Nintedanib Impurity F (Intermediate)
Catalogue No.	VQ-005385
CAS Number	2410649-54-4
IUPAC name	N-methyl-2-[4-[2-(N-methyl-4-nitroanilino)-2-oxoethyl]piperazin-1-yl]-N-(4-nitrophenyl)acetamide
Molecular formula	C₂₂H₂₆N₆O₆
Molecular weight	470.5 g/mol
Exact mass	470.1914
Grade	Reference Standard
HSN code	38229090
InChIKey	BBEPNUBQHPNLQJ-UHFFFAOYSA-N
SMILES	CN(C1=CC=C(C=C1)[N+](=O)[O-])C(=O)CN2CCN(CC2)CC(=O)N(C)C3=CC=C(C=C3)[N+](=O)[O-]
PubChem CID	36067683

Physical properties
Physical form	Solid
LogP (XLogP3)	1.9
H-bond donors / acceptors	0 / 8
TPSA	139 Å²
Synonyms	N1,N4-Dimethyl-N1,N4-bis(4-nitrophenyl)-1,4-piperazinediacetamide, 2,2'-(piperazine-1,4-diyl)bis(N-methyl-N-(4-nitrophenyl)acetamide), 2,2'-(Piperazine-1,4-diyl)bis(N-methyl-N-(4-nitrophenyl)acetamide) (Nintedanib Impurity), Nintedanib Impurity 52, 1,4-Piperazinediacetamide, N1,N4-dimethyl-N1,N4-bis(4-nitrophenyl)-, 1,?4-?Piperazinediacetamid?e, N1,?N4-?dimethyl-?N1,?N4-?bis(4-?nitrophenyl)?-

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Nintedanib Impurity F (Intermediate)?

The CAS Registry Number of Nintedanib Impurity F (Intermediate) is 2410649-54-4. It is also known as N1,N4-Dimethyl-N1,N4-bis(4-nitrophenyl)-1,4-piperazinediacetamide, 2,2'-(piperazine-1,4-diyl)bis(N-methyl-N-(4-nitrophenyl)acetamide), 2,2'-(Piperazine-1,4-diyl)bis(N-methyl-N-(4-nitrophenyl)acetamide) (Nintedanib Impurity).

What is the molecular formula and molecular weight of Nintedanib Impurity F (Intermediate)?

Nintedanib Impurity F (Intermediate) has the molecular formula C22H26N6O6 and a molecular weight of 470.5 g/mol. Its IUPAC name is N-methyl-2-[4-[2-(N-methyl-4-nitroanilino)-2-oxoethyl]piperazin-1-yl]-N-(4-nitrophenyl)acetamide.

What is Nintedanib Impurity F (Intermediate) used for?

Nintedanib Impurity F (Intermediate) is supplied as a characterised reference material related to Nintedanib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Nintedanib Impurity F (Intermediate) can I order?

We supply Nintedanib Impurity F (Intermediate) in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg, 500 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Nintedanib Impurity F (Intermediate)?

Yes. Every lot of Nintedanib Impurity F (Intermediate) is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Nintedanib Impurity F (Intermediate) be shipped internationally?

Yes. We export Nintedanib Impurity F (Intermediate) worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.