Cladribine EP Impurity B

About Cladribine EP Impurity B

Cladribine EP Impurity B is a pharmacopeial impurity of Cladribine carrying the CAS registry number 24757-70-8. With the molecular formula C11H15N5O4, it has a molar mass of 281.27 g/mol. Its systematic (IUPAC) name is (2R,3S,5R)-5-(6-amino-2-methoxypurin-9-yl)-2-(hydroxymethyl)oxolan-3-ol. It is also known as Cladribine - Impurity B or 2-Methoxy-2'-deoxyadenosine.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Good laboratory practice and suitable PPE are recommended during handling.

As a characterised impurity of Cladribine, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Cladribine

View every impurity, metabolite and intermediate we list for Cladribine.

Cladribine impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Cladribine EP Impurity B
Catalogue No.	VQ-022206
CAS Number	24757-70-8
IUPAC name	(2R,3S,5R)-5-(6-amino-2-methoxypurin-9-yl)-2-(hydroxymethyl)oxolan-3-ol
Molecular formula	C₁₁H₁₅N₅O₄
Molecular weight	281.27 g/mol
Exact mass	281.1124
Grade	Reference Standard
HSN code	38229090
InChIKey	HGRICISHTIAZJG-RRKCRQDMSA-N
SMILES	COC1=NC(=C2C(=N1)N(C=N2)[C@H]3C[C@@H]([C@H](O3)CO)O)N
PubChem CID	10265713

Physical properties
Physical form	Solid
LogP (XLogP3)	0.1
H-bond donors / acceptors	3 / 8
TPSA	129 Å²
Synonyms	Cladribine - Impurity B, 2-Methoxy-2'-deoxyadenosine, 2'-Deoxy-2-methoxyadenosine, Adenosine, 2'-deoxy-2-methoxy-, (2R,3S,5R)-5-(6-Amino-2-methoxy-9H-purin-9-yl)-2-(hydroxymethyl)tetrahydrofuran-3-ol, 2-Methoxy 2'-Deoxyadenosine, (2R,3S,5R)-5-(6-amino-2-methoxy-9H-purin-9-yl)-2-(hydroxymethyl)oxolan-3-ol, Adenosine, 2'-deoxy-2-methoxy- (8CI,9CI), 9-(2-Deoxy-beta-D-ribofuranosyl)-2-methoxyadenine, 2-Methoxy-6-amino-9-(2-deoxy-beta-D-erythro-pentofuranosyl)purine, (2R,3S,5R)-5-(6-amino-2-methoxy-purin-9-yl)-2-(hydroxymethyl)tetrahydrofuran-3-ol

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Cladribine EP Impurity B?

The CAS Registry Number of Cladribine EP Impurity B is 24757-70-8. It is also known as Cladribine - Impurity B, 2-Methoxy-2'-deoxyadenosine, 2'-Deoxy-2-methoxyadenosine.

What is the molecular formula and molecular weight of Cladribine EP Impurity B?

Cladribine EP Impurity B has the molecular formula C11H15N5O4 and a molecular weight of 281.27 g/mol. Its IUPAC name is (2R,3S,5R)-5-(6-amino-2-methoxypurin-9-yl)-2-(hydroxymethyl)oxolan-3-ol.

What is Cladribine EP Impurity B used for?

Cladribine EP Impurity B is supplied as a characterised reference material related to Cladribine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Cladribine EP Impurity B can I order?

We supply Cladribine EP Impurity B in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Cladribine EP Impurity B?

Yes. Every lot of Cladribine EP Impurity B is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Cladribine EP Impurity B be shipped internationally?

Yes. We export Cladribine EP Impurity B worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.