Apremilast EP Impurity E

About Apremilast EP Impurity E

Apremilast EP Impurity E is a pharmacopeial impurity of Apremilast carrying the CAS registry number 2487573-03-3. Formula C22H24N2O7S, molecular weight 460.5 g/mol. The IUPAC name is N-[2-[1-(4-ethoxy-3-methoxyphenyl)-2-methylsulfonylethyl]-1,3-dioxoisoindol-4-yl]acetamide. Common synonyms include Apremilast Impurity 175.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

Pharmaceutical QC and development laboratories use this impurity standard of Apremilast to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Apremilast EP Impurity E is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Apremilast

View every impurity, metabolite and intermediate we list for Apremilast.

Apremilast impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Apremilast EP Impurity E
Catalogue No.	VQ-021608
CAS Number	2487573-03-3
IUPAC name	N-[2-[1-(4-ethoxy-3-methoxyphenyl)-2-methylsulfonylethyl]-1,3-dioxoisoindol-4-yl]acetamide
Molecular formula	C₂₂H₂₄N₂O₇S
Molecular weight	460.5 g/mol
Exact mass	460.1304
Grade	Reference Standard
HSN code	38229090
InChIKey	RRQQEBWSUBCGRF-UHFFFAOYSA-N
SMILES	CCOC1=C(C=C(C=C1)C(CS(=O)(=O)C)N2C(=O)C3=C(C2=O)C(=CC=C3)NC(=O)C)OC
PubChem CID	176489833

Physical properties
Physical form	Solid
LogP (XLogP3)	1.8
H-bond donors / acceptors	1 / 7
TPSA	127 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Apremilast EP Impurity E?

The CAS Registry Number of Apremilast EP Impurity E is 2487573-03-3. It is also known as Apremilast Impurity 175.

What is the molecular formula and molecular weight of Apremilast EP Impurity E?

Apremilast EP Impurity E has the molecular formula C22H24N2O7S and a molecular weight of 460.5 g/mol. Its IUPAC name is N-[2-[1-(4-ethoxy-3-methoxyphenyl)-2-methylsulfonylethyl]-1,3-dioxoisoindol-4-yl]acetamide.

What is Apremilast EP Impurity E used for?

Apremilast EP Impurity E is supplied as a characterised reference material related to Apremilast. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Apremilast EP Impurity E can I order?

We supply Apremilast EP Impurity E in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Apremilast EP Impurity E?

Yes. Every lot of Apremilast EP Impurity E is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Apremilast EP Impurity E be shipped internationally?

Yes. We export Apremilast EP Impurity E worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.