Ribociclib N-Oxide (Piperzine N-Oxide)

About Ribociclib N-Oxide (Piperzine N-Oxide)

Ribociclib N-Oxide (Piperzine N-Oxide) is a metabolite or degradation product of Ribociclib carrying the CAS registry number 2514753-27-4. Formula C23H30N8O2, molecular weight 450.5 g/mol. Common synonyms include Ribociclib N-Oxide.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Good laboratory practice and suitable PPE are recommended during handling.

Analytical teams use this compound to identify metabolites and degradants of Ribociclib, to validate stability-indicating methods (AMV) and to support QC and regulatory filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Ribociclib N-Oxide (Piperzine N-Oxide) is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Ribociclib

View every impurity, metabolite and intermediate we list for Ribociclib.

Ribociclib impurities

Specifications & identifiers

Chemical identifiers
Product name	Ribociclib N-Oxide (Piperzine N-Oxide)
Catalogue No.	VQ-033528
CAS Number	2514753-27-4
IUPAC name	7-cyclopentyl-N,N-dimethyl-7-oxido-2-[(5-piperazin-1-yl-2-pyridinyl)amino]pyrrolo[2,3-d]pyrimidin-7-ium-6-carboxamide
Molecular formula	C₂₃H₃₀N₈O₂
Molecular weight	450.5 g/mol
Exact mass	450.2492
Grade	Reference Standard
HSN code	38229090
InChIKey	XOAHSLTUBMCUQZ-UHFFFAOYSA-N
SMILES	CN(C)C(=O)C1=CC2=CN=C(N=C2[N+]1(C3CCCC3)[O-])NC4=NC=C(C=C4)N5CCNCC5
PubChem CID	169436942

Physical properties
Physical form	Solid
LogP (XLogP3)	1.6
H-bond donors / acceptors	2 / 8
TPSA	104 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Ribociclib N-Oxide (Piperzine N-Oxide)?

The CAS Registry Number of Ribociclib N-Oxide (Piperzine N-Oxide) is 2514753-27-4. It is also known as Ribociclib N-Oxide.

What is the molecular formula and molecular weight of Ribociclib N-Oxide (Piperzine N-Oxide)?

Ribociclib N-Oxide (Piperzine N-Oxide) has the molecular formula C23H30N8O2 and a molecular weight of 450.5 g/mol. Its IUPAC name is 7-cyclopentyl-N,N-dimethyl-7-oxido-2-[(5-piperazin-1-yl-2-pyridinyl)amino]pyrrolo[2,3-d]pyrimidin-7-ium-6-carboxamide.

What is Ribociclib N-Oxide (Piperzine N-Oxide) used for?

Ribociclib N-Oxide (Piperzine N-Oxide) is supplied as a characterised reference material related to Ribociclib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Ribociclib N-Oxide (Piperzine N-Oxide) can I order?

We supply Ribociclib N-Oxide (Piperzine N-Oxide) in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Ribociclib N-Oxide (Piperzine N-Oxide)?

Yes. Every lot of Ribociclib N-Oxide (Piperzine N-Oxide) is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Ribociclib N-Oxide (Piperzine N-Oxide) be shipped internationally?

Yes. We export Ribociclib N-Oxide (Piperzine N-Oxide) worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.