2,5-Dioxopyrrolidin-1-yl ((3S,3aR,6aS)-hexahy… 253265-98-4

Name: 2,5-Dioxopyrrolidin-1-yl ((3S,3aR,6aS)-hexahydrofuro[2,3-b]furan-3-yl) carbonate
Brand: Vaqora Chemicals
SKU: VQ-030069

About 2,5-Dioxopyrrolidin-1-yl ((3S,3aR,6aS)-hexahydrofuro[2,3-b]furan-3-yl) carbonate

Vaqora Chemicals supplies 2,5-Dioxopyrrolidin-1-yl ((3S,3aR,6aS)-hexahydrofuro[2,3-b]furan-3-yl) carbonate, an impurity of Darunavir registered under CAS number 253265-98-4. Its molecular formula is C11H13NO7 and its molecular weight is 271.22 g/mol. Its systematic (IUPAC) name is [(3aR,4S,6aS)-2,3,3a,4,5,6a-hexahydrofuro[2,3-b]furan-4-yl] (2,5-dioxopyrrolidin-1-yl) carbonate. Alternative names: BIS THF HNS Derivative 1.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Good laboratory practice and suitable PPE are recommended during handling.

Pharmaceutical QC and development laboratories use this impurity standard of Darunavir to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

We offer 2,5-Dioxopyrrolidin-1-yl ((3S,3aR,6aS)-hexahydrofuro[2,3-b]furan-3-yl) carbonate in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Darunavir

View every impurity, metabolite and intermediate we list for Darunavir.

Darunavir impurities

Specifications & identifiers

Chemical identifiers
Product name	2,5-Dioxopyrrolidin-1-yl ((3S,3aR,6aS)-hexahydrofuro[2,3-b]furan-3-yl) carbonate
Catalogue No.	VQ-030069
CAS Number	253265-98-4
IUPAC name	[(3aR,4S,6aS)-2,3,3a,4,5,6a-hexahydrofuro[2,3-b]furan-4-yl] (2,5-dioxopyrrolidin-1-yl) carbonate
Molecular formula	C₁₁H₁₃NO₇
Molecular weight	271.22 g/mol
Exact mass	271.0692
Grade	Reference Standard
HSN code	38229090
InChIKey	VCFNCYVHQSHFRH-XSSZXYGBSA-N
SMILES	C1CO[C@@H]2[C@H]1[C@@H](CO2)OC(=O)ON3C(=O)CCC3=O
PubChem CID	11161570

Physical properties
Physical form	Solid
LogP (XLogP3)	-0.3
H-bond donors / acceptors	0 / 7
TPSA	91.4 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 2,5-Dioxopyrrolidin-1-yl ((3S,3aR,6aS)-hexahydrofuro[2,3-b]furan-3-yl) carbonate?

The CAS Registry Number of 2,5-Dioxopyrrolidin-1-yl ((3S,3aR,6aS)-hexahydrofuro[2,3-b]furan-3-yl) carbonate is 253265-98-4. It is also known as BIS THF HNS Derivative 1, 1-[[[[(3S,3aR,6aS)-Hexahydrofuro[2,3-b]furan-3-yl]oxy]carbonyl]oxy]-2,5-pyrrolidinedione, 2,5-Pyrrolidinedione, 1-[[[[(3S,3aR,6aS)-hexahydrofuro[2,3-b]furan-3-yl]oxy]carbonyl]oxy]-.

What is the molecular formula and molecular weight of 2,5-Dioxopyrrolidin-1-yl ((3S,3aR,6aS)-hexahydrofuro[2,3-b]furan-3-yl) carbonate?

2,5-Dioxopyrrolidin-1-yl ((3S,3aR,6aS)-hexahydrofuro[2,3-b]furan-3-yl) carbonate has the molecular formula C11H13NO7 and a molecular weight of 271.22 g/mol. Its IUPAC name is [(3aR,4S,6aS)-2,3,3a,4,5,6a-hexahydrofuro[2,3-b]furan-4-yl] (2,5-dioxopyrrolidin-1-yl) carbonate.

What is 2,5-Dioxopyrrolidin-1-yl ((3S,3aR,6aS)-hexahydrofuro[2,3-b]furan-3-yl) carbonate used for?

2,5-Dioxopyrrolidin-1-yl ((3S,3aR,6aS)-hexahydrofuro[2,3-b]furan-3-yl) carbonate is supplied as a characterised reference material related to Darunavir. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 2,5-Dioxopyrrolidin-1-yl ((3S,3aR,6aS)-hexahydrofuro[2,3-b]furan-3-yl) carbonate can I order?

We supply 2,5-Dioxopyrrolidin-1-yl ((3S,3aR,6aS)-hexahydrofuro[2,3-b]furan-3-yl) carbonate in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 2,5-Dioxopyrrolidin-1-yl ((3S,3aR,6aS)-hexahydrofuro[2,3-b]furan-3-yl) carbonate?

Yes. Every lot of 2,5-Dioxopyrrolidin-1-yl ((3S,3aR,6aS)-hexahydrofuro[2,3-b]furan-3-yl) carbonate is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 2,5-Dioxopyrrolidin-1-yl ((3S,3aR,6aS)-hexahydrofuro[2,3-b]furan-3-yl) carbonate be shipped internationally?

Yes. We export 2,5-Dioxopyrrolidin-1-yl ((3S,3aR,6aS)-hexahydrofuro[2,3-b]furan-3-yl) carbonate worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.