Hydroxy Bosentan

Name: Hydroxy Bosentan
Brand: Vaqora Chemicals
SKU: VQ-024069

About Hydroxy Bosentan

Listed under CAS 253688-60-7, Hydroxy Bosentan is a metabolite or degradation product of Bosentan available from Vaqora Chemicals. With the molecular formula C27H29N5O7S, it has a molar mass of 567.6 g/mol. It is also known as Bosentan Hydroxy or Bosentan metabolite Ro 48-5033.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Good laboratory practice and suitable PPE are recommended during handling.

It is used in metabolite identification, stability-indicating method development and impurity profiling of Bosentan, as well as in QC testing and ANDA/DMF documentation. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

We offer Hydroxy Bosentan in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Bosentan

View every impurity, metabolite and intermediate we list for Bosentan.

Bosentan impurities

Specifications & identifiers

Chemical identifiers
Product name	Hydroxy Bosentan
Catalogue No.	VQ-024069
CAS Number	253688-60-7
IUPAC name	N-[6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-2-pyrimidin-2-ylpyrimidin-4-yl]-4-(1-hydroxy-2-methylpropan-2-yl)benzenesulfonamide
Molecular formula	C₂₇H₂₉N₅O₇S
Molecular weight	567.6 g/mol
Exact mass	567.1788
Grade	Reference Standard
HSN code	38229090
InChIKey	FAJQMBCLPZWTQJ-UHFFFAOYSA-N
SMILES	CC(C)(CO)C1=CC=C(C=C1)S(=O)(=O)NC2=C(C(=NC(=N2)C3=NC=CC=N3)OCCO)OC4=CC=CC=C4OC
PubChem CID	6426755

Physical properties
Physical form	Solid
LogP (XLogP3)	2.6
H-bond donors / acceptors	3 / 12
TPSA	174 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Hydroxy Bosentan?

The CAS Registry Number of Hydroxy Bosentan is 253688-60-7. It is also known as Bosentan Hydroxy, Bosentan metabolite Ro 48-5033.

What is the molecular formula and molecular weight of Hydroxy Bosentan?

Hydroxy Bosentan has the molecular formula C27H29N5O7S and a molecular weight of 567.6 g/mol. Its IUPAC name is N-[6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-2-pyrimidin-2-ylpyrimidin-4-yl]-4-(1-hydroxy-2-methylpropan-2-yl)benzenesulfonamide.

What is Hydroxy Bosentan used for?

Hydroxy Bosentan is supplied as a characterised reference material related to Bosentan. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Hydroxy Bosentan can I order?

We supply Hydroxy Bosentan in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Hydroxy Bosentan?

Yes. Every lot of Hydroxy Bosentan is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Hydroxy Bosentan be shipped internationally?

Yes. We export Hydroxy Bosentan worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.